The transcription factor nuclear factor-kappa B and cancer

RO Escarcega, S Fuentes-Alexandro… - Clinical Oncology, 2007 - Elsevier
… signalling target of the TLRs is activation of the transcription factor NF-κB, a key regulator of
… kinase signalling cascades and thus activate multiple transcription factors [18]. NF-κB has …

Nuclear factor kappa B: important transcription factor and therapeutic target

JI Lee, GJ Burckart - The Journal of clinical pharmacology, 1998 - Wiley Online Library
Nuclear factor kappa B (NF-KB) is an ubiquitous rapid response transcription factor in cells
… , chemokines, cell adhesion molecules, growth factors, and immunoreceptors. In this manner, …

Activated transcription factor nuclear factor-kappa B is present in the atherosclerotic lesion.

K Brand, S Page, G Rogler, A Bartsch… - The Journal of …, 1996 - Am Soc Clin Investig
… This study demonstrates the presence of activated NF- B transcription factor in the human
atherosclerotic lesion in smooth muscle cells, macrophages, and endothelial cells. …

Nuclear transcription factor NF-kappa B: role in biology and medicine

BB Aggarwal, Y Takada, S Shishodia, AM Gutierrez… - 2004 - nopr.niscpr.res.in
… The inducible transcription factor nuclear factor-kappa B (NF-KB) plays a central role in
regulation of many immune, inflammatory and carcinogenic responses. While normal activation …

The role of the transcription factor nuclear factor-kappa B in thyroid autoimmunity and cancer

C Giuliani, I Bucci, G Napolitano - Frontiers in endocrinology, 2018 - frontiersin.org
transcription factors that have a TAD. Otherwise, p50 and p52 can bind as homodimers and
repress gene transcription by … the NF-κB family of transcription factors as a whole (as given in …

Transcription factor nuclear factor-kappa B is activated in neurons after focal cerebral ischemia

D Stephenson, T Yin, EB Smalstig… - Journal of Cerebral …, 2000 - journals.sagepub.com
Nuclear factor-kappa B (NF-kB) is a multisubunit transcription factor that when activated
induces the expression of genes encoding acute-phase proteins, cell adhesion molecules, cell …

Nuclear factor kappa-B and the heart

G Valen, Z Yan, GK Hansson - Journal of the American College of …, 2001 - jacc.org
… -B (NFκB) is a redox-sensitive transcription factor regulating a battery of inflammatory
genes; it has been implicated as important for initiation and progression of pathogenesis in …

A secreted/shed product of Helicobacter pylori activates transcription factor nuclear factor-kappa B.

A Münzenmaier, C Lange, E Glocker… - … (Baltimore, Md.: 1950 …, 1997 - journals.aai.org
… pylori-mediated IL-8 secretion requires activation of the transcription factor nuclear factor-…
all IL-binducing strains activate the transcription factor. Moreover, the antioxidant curcumin, …

Role of nuclear factorkappa B in atherogenesis

K Brand, S Page, AK Walli, D Neumeier… - Experimental …, 1997 - Wiley Online Library
Transcription factors of the nuclear factor-KcB (NF-KcB)/Rel … strongly indicate that the inducible
transcription factor NF-KB is … transcription factor in human chronic inflammatory disease. …

Nuclear factor kappa B signaling complexes in acute inflammation

S Rius-Pérez, S Pérez, P Martí-Andrés… - Antioxidants & redox …, 2020 - liebertpub.com
… p65 and nuclear factor erythroid 2-related factor 2 (NRF2) compete for binding to coactivator
… Critical Issues: NF-κB is a redox-sensitive transcription factor that forms specific signaling …