Factors underlying variable DNA methylation in a human community cohort

LL Lam, E Emberly, HB Fraser… - Proceedings of the …, 2012 - National Acad Sciences
… -specific DNA methylation. Next, we examined whether highly variable DNA methylation was
… gene expression, suggesting that variable DNA methylation was not obligatorily transmitted …

Variable DNA methylation is associated with chronic obstructive pulmonary disease and lung function

W Qiu, A Baccarelli, VJ Carey, N Boutaoui… - American journal of …, 2012 - atsjournals.org
… of DNA methylation marks in subjects with and without a history of COPD may provide insights
into the variable … To pursue this hypothesis we conducted methylation screens, using the …

Variable DNA methylation patterns associated with progression of disease in hepatocellular carcinomas

W Gao, Y Kondo, L Shen, Y Shimizu, T Sano… - …, 2008 - academic.oup.com
DNA methylation analysis in representative 24 identified genes in 38 HCC patients and
assessed the relationship between DNA methylation … that aberrant DNA methylation is a frequent …

Characterizing genetic and environmental influences on variable DNA methylation using monozygotic and dizygotic twins

E Hannon, O Knox, K Sugden, J Burrage… - PLoS …, 2018 - journals.plos.org
… Given these contextual differences, we tested whether genetic and environmental contributions
to variable DNA methylation differ across genomic domains. As DNAm sites located in …

Genome-wide identification of inter-individually variable DNA methylation sites improves the efficacy of epigenetic association studies

T Hachiya, R Furukawa, Y Shiwa, H Ohmomo… - NPJ genomic …, 2017 - nature.com
variable CpG sites will accelerate the discovery of clinically relevant DNA methylation
From this perspective, locus-specific DNA methylation (DNAm) signatures in blood cells have …

Mapping of variable DNA methylation across multiple cell types defines a dynamic regulatory landscape of the human genome

J Gu, M Stevens, X Xing, D Li, B Zhang… - G3: Genes …, 2016 - academic.oup.com
… of transcription factor binding and variable DNA methylation, we calculated the fold enrichment
of … All the evidence supports potential interactions between variable DNA methylation and …

Regions of variable DNA methylation in human placenta associated with newborn neurobehavior

AG Paquette, EA Houseman, BB Green, C Lesseur… - Epigenetics, 2016 - Taylor & Francis
… Candidate gene studies identified variation in placental DNA methylation is associated with
… We sought to identify novel regions of variable DNA methylation associated with newborn …

Identification of type 1 diabetes–associated DNA methylation variable positions that precede disease diagnosis

VK Rakyan, H Beyan, TA Down, MI Hawa… - PLoS …, 2011 - journals.plos.org
… first screen show intra-MZ pair DNA methylation differences in the expected direction. Indeed,
we observed a statistically significant DNA methylation difference in the expected direction …

A statistical method for excluding non-variable CpG sites in high-throughput DNA methylation profiling

H Meng, AR Joyce, DE Adkins, P Basu, Y Jia, G Li… - BMC …, 2010 - Springer
… To test for association between DNA methylation variables and lung function decline outcome
variables, we performed regression analyses with the probes as predictor variables. The F-…

The relationship between DNA methylation, genetic and expression inter-individual variation in untransformed human fibroblasts

JR Wagner, S Busche, B Ge, T Kwan, T Pastinen… - Genome biology, 2014 - Springer
… there is a genetic component to both variable DNA methylation and gene expression, as
well as genome-level differences in gene expression linked to DNA methylation, the combined …