Dendrimers for drug delivery

AS Chauhan - Molecules, 2018 - mdpi.com
… Application of dendrimers as a drug delivery system started … performance because of
low water solubility and hence low … solubility enhancement propensity of dendrimers [2,9,10]. …

Dendrimers as potential drug carriers; encapsulation of acidic hydrophobes within water soluble PAMAM derivatives

AE Beezer, ASH King, IK Martin, JC Mitchel… - Tetrahedron, 2003 - Elsevier
… a drug delivery system). We therefore, decided to synthesise a series of neutral water soluble
dendrimers… were simple derivatives of commercially available PAMAM dendrimers (Fig. 1). …

Solubilization and release properties of dendrimers. Evaluation as prospective drug delivery systems

L Fernandez, M Gonzalez, H Cerecetto… - Supramolecular …, 2006 - Taylor & Francis
… In addition the prospective application of the dendrimers as drug carriers was evaluated by
… very low water solubility, which limits their application. Polypropylene imine dendrimers with …

The synthesis of water soluble dendrimers, and their application as possible drug delivery systems

LJ Twyman, AE Beezer, R Esfand, MJ Hardy… - Tetrahedron …, 1999 - Elsevier
water soluble dendrimers using a modified PAMAM synthesis. Additionally, we have
demonstrated that these water soluble dendrimers … complex's infinite water solubility, the solubility

Dendrimers: emerging polymers for drug-delivery systems

BK Nanjwade, HM Bechra, GK Derkar, FV Manvi… - … of Pharmaceutical …, 2009 - Elsevier
Dendrimers are new class of polymeric materials. It is generally described as a … with these
dendrimers such as uniform size, high degree of branching, water solubility, multivalency, well-…

Dendrimers as drug carriers: applications in different routes of drug administration

Y Cheng, Z Xu, M Ma, T Xu - Journal of pharmaceutical sciences, 2008 - Elsevier
… of dendrimers. These specific properties make dendrimers suitable for drug delivery systems.
… However, poor water solubility of many drugs, especially anti‐cancer drugs, limits the …

Introduction for design of nanoparticle based drug delivery systems

J Yan Chan Edgar, H Wang - Current Pharmaceutical Design, 2017 - ingentaconnect.com
drug delivery systems contain numerous limitations such as limited targeting, low therapeutic
indices, poor water solubility, and the induction of drugdendrimer drug delivery systems: a …

Dendrimers in drug-delivery applications

Q Lin, G Jiang, K Tong - Designed Monomers and Polymers, 2010 - Taylor & Francis
… of the dendrimers or conjugated onto the dendrimer surface. … quite a few drugs have low
water solubility or cell membrane … the development of dendrimer-based drug-delivery systems. …

Dendrimers as versatile platform in drug delivery applications

S Svenson - European Journal of Pharmaceutics and …, 2009 - Elsevier
water solubility; however, mixing with PAMAM dendrimers (8.0 mM) containing a primary
amine surface significantly enhanced the water solubility … is an active transport system. Specific …

Dendrimers in drug delivery

M Markowicz-Piasecka, E Mikiciuk-Olasik - … in Drug Delivery, 2016 - Elsevier
… There are many scientists’ conclusions that the dendrimer-based transdermal delivery
system of NSAIDs could be explored as an attractive approach for treating various ailments and …