Human DNA methylomes at base resolution show widespread epigenomic differences

R Lister, M Pelizzola, RH Dowen, RD Hawkins, G Hon… - nature, 2009 - nature.com
… found extensive differences between the DNA methylomes of two human cell types, revealing
the highly dynamic nature of this epigenetic modification. The genomic context of the DNA

Exposing the DNA methylome iceberg

MN Ndlovu, H Denis, F Fuks - Trends in biochemical sciences, 2011 - cell.com
DNA methylation was the first epigenetic modification discovered. Until recently, … of DNA
methylation in different cell states or phenotypes. The emerging picture includes extensive gene …

“Same difference”: comprehensive evaluation of four DNA methylation measurement platforms

TJ Kacmarczyk, MP Fall, X Zhang, Y Xin, Y Li… - Epigenetics & …, 2018 - Springer
differences of these four methods considering each platform targets approximately 10–13%
of the human methylome… the Human Epigenomics Roadmap [10] have performed extensive

A comprehensive analysis of 195 DNA methylomes reveals shared and cell-specific features of partially methylated domains

A Salhab, K Nordström, G Gasparoni, K Kattler, P Ebert… - Genome biology, 2018 - Springer
comparison, we wanted to monitor the impact of cultivation and cancer-specific changes on
PMD formation. We generated epigenomeDNA methylation is the consequence of extensive

Widespread natural variation of DNA methylation within angiosperms

CE Niederhuth, AJ Bewick, L Ji, MS Alabady, KD Kim… - Genome biology, 2016 - Springer
… a comparative epigenomics study of 34 angiosperms (flowering plants). Differences in mCG
… To test this hypothesis, we examined a DNA methylome of a parental M. esculenta plant that …

[HTML][HTML] The DNA methylome

M Pelizzola, JR Ecker - FEBS letters, 2011 - Elsevier
DNA methylomes for several organisms are now available, helping clarify the evolutionary
story of this epigenetic … absent in differentiated cells, widespread differences were found in the …

[PDF][PDF] Mapping the methylome

EV Epigenomics - Cell Cycle, 2006 - researchgate.net
… Using this method, one of the primary epigenetic differences … gain in combination with
extensive demethylation is a potential … epigenetic components, and would thus benefit from this …

Human DNA methylomes of neurodegenerative diseases show common epigenomic patterns

JV Sanchez-Mut, H Heyn, E Vidal, S Moran… - Translational …, 2016 - nature.com
… We found significant differences in the DNA methylation patterns between the control gray
… from four prevalent neurodegenerative disorders. We subtracted the DNA methylome of the …

Cancer epigenomics: DNA methylomes and histone-modification maps

M Esteller - Nature reviews genetics, 2007 - nature.com
… How many genes undergo epigenetic disruption in a given tumour? Do these changes differ
… genome-wide profiles for an extensive range of epigenetic marks in various human cell …

Obligatory and facilitative allelic variation in the DNA methylome within common disease-associated loci

CG Bell, F Gao, W Yuan, L Roos, RJ Acton… - Nature …, 2018 - nature.com
… -seq peripheral-blood DNA methylomes, we find 7173 consistent … strong DNA methylation
allelic differences driven by … that regional epigenetic effects exist within the DNA methylome 15 …