Global changes in genomic methylation levels during early development of the zebrafish embryo
AA Mhanni, RA McGowan - Development genes and evolution, 2004 - Springer
… the methylation status of the zebrafish genome during early embryogenesis and we find
evidence that methylation fluxes do occur in that organism. The parental genetic contributions to …
evidence that methylation fluxes do occur in that organism. The parental genetic contributions to …
[HTML][HTML] Developmental features of DNA methylation during activation of the embryonic zebrafish genome
… Xenopus embryos retain a high methylation level … methylation -1 to 0 kb of the TSS in
zebrafish embryos, indicating that promoter DNA methylation is not a key determinant of embryonic …
zebrafish embryos, indicating that promoter DNA methylation is not a key determinant of embryonic …
DNA methylation profiling in zebrafish
… methylation levels genome-wide in zebrafish: one is an established method for revealing
regional methylation (methylated … To extract genomic DNA from zebrafish adult tissue, embryos, …
regional methylation (methylated … To extract genomic DNA from zebrafish adult tissue, embryos, …
Absence of genome-wide changes in DNA methylation during development of the zebrafish
D Macleod, VH Clark, A Bird - Nature genetics, 1999 - nature.com
… leads to local transcriptional repression and is essential for normal development in the … by
changes in global levels of DNA methylation 2,3 . Methylation levels are lowest in blastocyst …
changes in global levels of DNA methylation 2,3 . Methylation levels are lowest in blastocyst …
Global and gene specific DNA methylation changes during zebrafish development
X Fang, J Corrales, C Thornton, BE Scheffler… - … and Physiology Part B …, 2013 - Elsevier
… gene specific DNA methylation in zebrafish (Danio rerio) embryos, larvae and … genome-wide
methylation reprogramming occurs in PGCs after sex determination. The methylation level …
methylation reprogramming occurs in PGCs after sex determination. The methylation level …
Embryonic DNA methylation: insights from the genomics era
O Bogdanović… - … in functional genomics, 2014 - academic.oup.com
… global genomic DNA methylation levels in the DNA obtained from early embryonic lineages.
… In the zebrafish embryo, the maternal genomic contribution becomes extensively remodeled …
… In the zebrafish embryo, the maternal genomic contribution becomes extensively remodeled …
Zebrafish embryos as a screen for DNA methylation modifications after compound exposure
MC Bouwmeester, S Ruiter, T Lommelaars… - Toxicology and applied …, 2016 - Elsevier
… corrected methylation levels were available for 64,466 sites mapped to the zebrafish genome…
Generally, the data quality was good, as was illustrated by the uniform methylation levels at …
Generally, the data quality was good, as was illustrated by the uniform methylation levels at …
Effects on specific promoter DNA methylation in zebrafish embryos and larvae following benzo [a] pyrene exposure
… in promoter DNA methylation in zebrafish whole embryos and larvae following a … , genome-wide
demethylation occurs after sex determination (Popp et al., 2010). The methylation level …
demethylation occurs after sex determination (Popp et al., 2010). The methylation level …
Genome-wide DNA methylation profiling in zebrafish
… Zebrafish embryos and activated oocytes have a high level of lipid content within the yolk,
which we find inhibits DNA extraction. Thus, we performed nuclei purification prior to lysis. …
which we find inhibits DNA extraction. Thus, we performed nuclei purification prior to lysis. …
Immunological detection of changes in genomic DNA methylation during early zebrafish development
AB MacKay, AA Mhanni, RA McGowan, PH Krone - Genome, 2007 - cdnsciencepub.com
… to the broad reduction in genomic methylation in cleavage-stage zebrafish embryos we have
… unaffected during periods of overall genomic DNA demethylation (Santos and Dean 2004). …
… unaffected during periods of overall genomic DNA demethylation (Santos and Dean 2004). …
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