Global changes in genomic methylation levels during early development of the zebrafish embryo

AA Mhanni, RA McGowan - Development genes and evolution, 2004 - Springer
… the methylation status of the zebrafish genome during early embryogenesis and we find
evidence that methylation fluxes do occur in that organism. The parental genetic contributions to …

[HTML][HTML] Developmental features of DNA methylation during activation of the embryonic zebrafish genome

IS Andersen, AH Reiner, H Aanes, P Aleström, P Collas - Genome biology, 2012 - Springer
… Xenopus embryos retain a high methylation levelmethylation -1 to 0 kb of the TSS in
zebrafish embryos, indicating that promoter DNA methylation is not a key determinant of embryonic

DNA methylation profiling in zebrafish

SF Wu, H Zhang, SS Hammoud, M Potok, DA Nix… - Methods in cell …, 2011 - Elsevier
methylation levels genome-wide in zebrafish: one is an established method for revealing
regional methylation (methylated … To extract genomic DNA from zebrafish adult tissue, embryos, …

Absence of genome-wide changes in DNA methylation during development of the zebrafish

D Macleod, VH Clark, A Bird - Nature genetics, 1999 - nature.com
… leads to local transcriptional repression and is essential for normal development in the … by
changes in global levels of DNA methylation 2,3 . Methylation levels are lowest in blastocyst …

Global and gene specific DNA methylation changes during zebrafish development

X Fang, J Corrales, C Thornton, BE Scheffler… - … and Physiology Part B …, 2013 - Elsevier
… gene specific DNA methylation in zebrafish (Danio rerio) embryos, larvae and … genome-wide
methylation reprogramming occurs in PGCs after sex determination. The methylation level

Embryonic DNA methylation: insights from the genomics era

O Bogdanović… - … in functional genomics, 2014 - academic.oup.com
… global genomic DNA methylation levels in the DNA obtained from early embryonic lineages.
… In the zebrafish embryo, the maternal genomic contribution becomes extensively remodeled …

Zebrafish embryos as a screen for DNA methylation modifications after compound exposure

MC Bouwmeester, S Ruiter, T Lommelaars… - Toxicology and applied …, 2016 - Elsevier
… corrected methylation levels were available for 64,466 sites mapped to the zebrafish genome
Generally, the data quality was good, as was illustrated by the uniform methylation levels at …

Effects on specific promoter DNA methylation in zebrafish embryos and larvae following benzo [a] pyrene exposure

J Corrales, X Fang, C Thornton, W Mei… - … and Physiology Part C …, 2014 - Elsevier
… in promoter DNA methylation in zebrafish whole embryos and larvae following a … , genome-wide
demethylation occurs after sex determination (Popp et al., 2010). The methylation level

Genome-wide DNA methylation profiling in zebrafish

PJ Murphy, BR Cairns - Methods in Cell Biology, 2016 - Elsevier
Zebrafish embryos and activated oocytes have a high level of lipid content within the yolk,
which we find inhibits DNA extraction. Thus, we performed nuclei purification prior to lysis. …

Immunological detection of changes in genomic DNA methylation during early zebrafish development

AB MacKay, AA Mhanni, RA McGowan, PH Krone - Genome, 2007 - cdnsciencepub.com
… to the broad reduction in genomic methylation in cleavage-stage zebrafish embryos we have
… unaffected during periods of overall genomic DNA demethylation (Santos and Dean 2004). …