Development of cancer is associated with activation of blood coagulation. The results of
laboratory tests clearly demonstrate that fibrin formation and dissolution is continuously …

The relationship between increased clotting and malignancy is well recognized, though the
bidirectional development of this association is often overlooked. In the challenging cancer …

Pathological activation of the coagulation system occurs with virtually all forms of cancer,
particularly epithelial malignancies. Accordingly, thrombosis is one of the most common …

The interactions between components of the hemostatic system and cancer cells are
multifaceted. Strong clinical evidence is accumulating on the prothrombotic tendency of …

Cancer cells can contribute to activation of the clotting system by their capacity to produce
and release procoagulant/fibrinolytic substances and inflammatory cytokines, and by their …

Thrombosis is a major cause of morbidity and mortality in cancer patients. The pathogenesis
of blood coagulation activation in oncological patients is complex and involves both clinical …

Thrombosis and disseminated intravascular coagulation (DIC) are common complications in
cancer. Patients with malignancy have a prothrombotic state due to the ability of almost all …

Pathogenesis of the prothrombotic state of cancer patients is due, at least in part, to the
ability of cancer cells to activate the coagulation system. Several complex and not fully …

Malignancy affects the hemostatic system and the hemostatic system affects malignancy. In
cancer patients there are a number of coagulation abnormalities which provide the …

The close relationship between cancer and thrombosis is known since more than a century.
Venous thromboembolism (VTE) may be the first manifestation of an occult malignancy in an …