Hepatocyte nuclear factor 4α (HNF4α) plays an important role in the maintenance of many
liver-specific functions. Liver-specific HNF4α-null mice were used to determine whether …

The human coagulation protease factor VII plays a pivotal role in the initiation of the
coagulation cascade by both the extrinsic and the intrinsic pathway. Although the gene …

Abstract Hepatocyte nuclear factor 4 (HNF4) was first identified as a DNA binding activity in
rat liver nuclear extracts. Protein purification had then led to the cDNA cloning of rat HNF4 …

Hepatocyte nuclear factor 4 (HNF-4) is an essential positive regulator of a large number of
liver-specific genes. We report here the isolation of three HNF-4 isoforms from a human liver …

HNF1 is a transcription factor that is required for hepatocyte-specific expression of several
genes, including albumin and fibrinogen. Rat HNF1-encoding cDNAs have recently been …

Hepatocyte nuclear factor 4 (HNF-4) is a liver-enriched transcription factor involved in the
expression of many liver-specific genes. In the preceding communication (Hata, S …

Hepatocyte nuclear factor 4-α (HNF4-α) regulates expression of a number of genes in
several metabolic organs. The HNF4-α gene has two promoters and encodes at least nine …

Factor XII (FXII) is a liver-specific zymogen involved in the regulation of hemostasis,
particularly in the activation of fibrinolysis. Transcription of the FXII gene is stimulated by …

To identify the 5′ sequences of the murine coagulation factor VII (fVII) gene that resulted in
its efficient transcription, a variety of 5′-flanking sequences up to 7 kilobase pairs upstream …

Abstract Hepatocyte nuclear factor 4 (HNF-4) is a key transcription factor involved in the
specific expression of many genes in liver and intestine. Sequences of cDNAs coding for …