Factor VII is a vitamin K-dependent coagulation protein essential for proper hemostasis. The
human Factor VII gene spans 13 kilobase pairs and is located on chromosome 13 just 2.8 …

Factor VII is a vitamin K-dependent zymogen of a serine protease that participates in the
initial phase of blood coagulation. A factor VII molecular variant (factor VII Central) was …

Activated factor VII (factor VIIa) is a vitamin K-dependent plasma serine protease that
participates in a cascade of reactions leading to the coagulation of blood. Two overlapping …

Two alternative pathways exist for the activation of factor X, a step required to convert
prothrombin to thrombin in the later stages of the coagulation cascade. In the intrinsic …

Promoter and silencer elements of the immediate 5'flanking region of the gene coding for
human factor VII were identified and characterized. The major transcription start site …

To facilitate studies of the in vivo role of the extrinsic pathway of coagulation in experimental
hemostasis and thrombosis, a full-length cDNA-encoding rabbit factor VII was isolated using …

Factor VII is a vitamin K‐dependent coagulation protease essential for the initiation phase of
normal hemostasis. The human factor VII gene (FVII, also known as F7) spans 13 kb and is …

Factor VII is a precursor to a serine protease that is present in mammalian plasma. In its
activated form, it participates in blood coagulation by activating factor X and/or factor IX in …

Factor X is a vitamin K-dependent glycoprotein that plays an essential role in both the
intrinsic and extrinsic pathways of blood coagulation. Studies on a recombinant lambda …

Factor VII is a multidomain, vitamin K-dependent plasma glycoprotein that participates in the
extrinsic pathway of blood coagulation. Earlier studies demonstrated a novel disaccharide …