The human immunodeficiency virus type-1 (HIV-1) regulatory protein Tat is produced in the
early phase of infection and is essential for virus replication. Together with other viral …

Microglia are activated in humans following infection with human immunodeficiency virus
(HIV), and brain inflammation is thought to be involved in neuronal injury and dysfunction …

Human immunodeficiency virus (HIV) infection may cause a dementing illness. HIV-
mediated dementia is clinically and pathologically correlated with the infiltration of activated …

The pathological correlates of dementia due to human immunodeficiency virus (HIV)
infection are glial cell activation and cytokine dysregulation. These findings occur in the …

The interaction of human immunodeficiency virus type 1 (HIV-1) with CD4+ T lymphocytes is
well studied and typically results in virally induced cytolysis. In contrast, relatively little is …

To determine the role of the Tat protein of the human immunodeficiency virus type 1 (HIV-1)
in the pathogenesis of HIV-1 associated dementia, recombinant Tat was injected …

The human immunodeficiency virus (HIV)-Tat protein has been implicated in the
neuropathogenesis of HIV infection. However, its role in modulating astroglial-neuronal …

We have studied the modulation of cyclic AMP (cAMP) accumulation by the human
immunodeficiency virus type 1 (HIV 1) protein Tat in microglia and astrocyte cultures …

The human immunodeficiency virus type 1 (HIV-1) Tat protein is a key pathogenic factor in a
variety of acquired immune deficiency syndrome (AIDS)-associated disorders. A number of …

The acquired immunodeficiency syndrome (AIDS) frequently involves the central nervous
system (CNS) and manifests as dementia due to encephalitis or diffuse neurodegeneration …