[HTML][HTML] Pathways of epoxyeicosatrienoic acid metabolism in endothelial cells: implications for the vascular effects of soluble epoxide hydrolase inhibition
X Fang, TL Kaduce, NL Weintraub, S Harmon… - Journal of Biological …, 2001 - ASBMB
Epoxyeicosatrienoic acids (EETs) are products of cytochrome P-450 epoxygenase that
possess important vasodilating and anti-inflammatory properties. EETs are converted to the …
possess important vasodilating and anti-inflammatory properties. EETs are converted to the …
Inhibition of soluble epoxide hydrolase by trans-4-[4-(3-adamantan-1-yl-ureido)-cyclohexyloxy]-benzoic acid is protective against ischemia–reperfusion injury
KR Chaudhary, M Abukhashim… - Journal of …, 2010 - journals.lww.com
Arachidonic acid, a polyunsaturated fatty acid, can be metabolized to cardioprotective
epoxyeicosatrienoic acids (EETs) by cytochrome P450 epoxygenases, which are …
epoxyeicosatrienoic acids (EETs) by cytochrome P450 epoxygenases, which are …
Cytochrome P450 eicosanoids and cerebral vascular function
The eicosanoids 20-hydroxyeicosatetraenoic acid (20-HETE) and epoxyeicosatrienoic acids
(EETs), which are generated from the metabolism of arachidonic acid by cytochrome P450 …
(EETs), which are generated from the metabolism of arachidonic acid by cytochrome P450 …
Epoxyeicosatrienoic acids are part of the VEGF-activated signaling cascade leading to angiogenesis
AC Webler, UR Michaelis, R Popp… - … of Physiology-Cell …, 2008 - journals.physiology.org
Cytochrome P-450 (CYP) epoxygenases metabolize arachidonic acid to
epoxyeicosatrienoic acid (EET) regioisomers, which activate several signaling pathways to …
epoxyeicosatrienoic acid (EET) regioisomers, which activate several signaling pathways to …
Cytochrome P450 pathways of arachidonic acid metabolism
Cytochrome P450s metabolize arachidonic acid to hydroxyeicosatetraenoic acids and
epoxyeicosatrienoic acids. These eicosanoids are formed in a tissue and cell-specific …
epoxyeicosatrienoic acids. These eicosanoids are formed in a tissue and cell-specific …
α-and β-alkyl-substituted eicosapentaenoic acids: Incorporation into phospholipids and effets on prostaglandin H synthase and 5-lipoxygenase
LN Larsen, J Bremer, S Flock, L Skattebøl - Biochemical Pharmacology, 1998 - Elsevier
α-ethyl-, α-methyl-and β-methyl eicosapentaenoic acid (EPA) were prepared and their
incorporation into cell lipids and effects on eicosanoid synthesis compared with EPA and …
incorporation into cell lipids and effects on eicosanoid synthesis compared with EPA and …
Endothelial control of vasodilation: integration of myoendothelial microdomain signalling and modulation by epoxyeicosatrienoic acids
DC Ellinsworth, S Earley, TV Murphy… - Pflügers Archiv-European …, 2014 - Springer
Endothelium-derived epoxyeicosatrienoic acids (EETs) are fatty acid epoxides that play an
important role in the control of vascular tone in selected coronary, renal, carotid, cerebral …
important role in the control of vascular tone in selected coronary, renal, carotid, cerebral …
[HTML][HTML] 20-Hydroxyeicosatetraenoic acid contributes to the inhibition of K+ channel activity and vasoconstrictor response to angiotensin II in rat renal microvessels
The present study examined whether 20-hydroxyeicosatetraenoic acid (HETE) contributes to
the vasoconstrictor effect of angiotensin II (ANG II) in renal microvessels by preventing …
the vasoconstrictor effect of angiotensin II (ANG II) in renal microvessels by preventing …
Role of 20-hydroxyeicosatetraenoic acid and epoxyeicosatrienoic acids in hypertension
A Sarkis, B Lopez, RJ Roman - Current opinion in nephrology and …, 2004 - journals.lww.com
Role of 20-hydroxyeicosatetraenoic acid and epoxyeicosatrien... : Current Opinion in
Nephrology and Hypertension Role of 20-hydroxyeicosatetraenoic acid and …
Nephrology and Hypertension Role of 20-hydroxyeicosatetraenoic acid and …
20-Hydroxyeicosatetraenoic acid mediates calcium/calmodulin-dependent protein kinase II-induced mitogen-activated protein kinase activation in vascular smooth …
MM Muthalif, IF Benter, N Karzoun… - Proceedings of the …, 1998 - National Acad Sciences
Norepinephrine (NE) and angiotensin II (Ang II), by promoting extracellular Ca2+ influx,
increase Ca2+/calmodulin-dependent kinase II (CaMKII) activity, leading to activation of …
increase Ca2+/calmodulin-dependent kinase II (CaMKII) activity, leading to activation of …