Endothelium-derived epoxyeicosatrienoic acids (EETs) are fatty acid epoxides that play an
important role in the control of vascular tone in selected coronary, renal, carotid, cerebral …

We hypothesized that shear stress stimulates the release of epoxyeicosatrienoic acids
(EETs) from arteriolar endothelium, which directly hyperpolarize smooth muscle. To test this …

Epoxyeicosatrienoic acids (EETs) are cytochrome P450 metabolites of arachidonic acid that
are produced by the vascular endothelium in response to agonists such as bradykinin and …

Myocardial perfusion and coronary vascular resistance are regulated by signaling
metabolites released from the local myocardium that act either directly on the VSMC or …

In addition to their contribution to endothelium‐derived hyperpolarization, our understanding
of the physiological function of epoxyeicosatrienoic acids (EET) within the vascular wall and …

Endothelium-dependent hyperpolarization and relaxation of vascular smooth muscle are
mediated by endothelium-derived hyperpolarizing factors (EDHFs). EDHF candidates …

Epoxyeicosatrienoic acids (EETs) are generated from arachidonic acid by cytochrome P450
(CYP) epoxygenases. The expression of CYP epoxygenases in endothelial cells is …

Epoxyeicosatrienoic acids (EETs) are epoxides of arachidonic acid generated by
cytochrome P450 (CYP) epoxygenases. The activation of CYP epoxygenases in endothelial …

Epoxyeicosatrienoic acids (EETs) are cytochrome P450-derived metabolites of arachidonic
acid that function as endothelium-derived hyperpolarizing factors (EDHFs) in many species …

The endothelium regulates vascular tone through the release of a number of soluble
mediators, including NO, prostaglandin I2, and endothelium-derived hyperpolarizing factor …