The pedunculopontine (PPN) region of the upper brainstem is recognized as a critical
modulator of activated behavioral states such as wakefulness and rapid eye movement …

There is a consensus that active sleep (AS; ie, REM sleep) is produced by cholinergic
projections from the pedunculopontine tegmental nuclei (PPT) that activate AS-on neurons …

The oral pontine reticular formation (PnO) of rat is one region identified in the brainstem as a
rapid eye movement (REM) sleep induction zone. Microinjection of GABA A receptor …

This study tested the hypothesis that cholinoceptive regions of the medial pontine reticular
formation (mPRF), long known to play a role in regulating the sleep cycle, can also causally …

The purpose of this study was to determine whether neurons in the medial pontine reticular
formation with high discharge rates during REM sleep could be localized in regions of the …

The brainstem contains the neural systems that are necessary for the generation of the state
of paradoxical sleep (PS) and accompanying muscle atonia. Important for its initiation are …

Cholinergic microstimulation of the ventral part of the oral pontine reticular nucleus (vRPO)
in cats generates and maintains paradoxical sleep. The implication of rostral raphe nuclei in …

The hypothesis that REM sleep is cholinergically mediated is supported by the identification
of a cholinoceptive trigger zone in the FTG. Since this trigger zone is devoid of cholinergic …

Intracellular recording of medial pontine reticular formation (mPRF) neurons in behaving
cats show the following distinctive desynchronized sleep (D) state characteristics: excitability …

The percent of rapid eye movement (REM) sleep decreases dramatically between 10 and 30
days postnatally in the rat. The pedunculopontine nucleus (PPN) is known to modulate …