Alpha-2 adrenergic regulation of pedunculopontine nucleus neurons during development

KD Bay, K Mamiya, CH Good, RD Skinner… - Neuroscience, 2006 - Elsevier
Rapid eye movement sleep decreases between 10 and 30 days postnatally in the rat. The
pedunculopontine nucleus is known to modulate waking and rapid eye movement sleep …

Carbachol models of REM sleep: recent developments and new directions.

L Kubin - Archives italiennes de biologie, 2001 - architalbiol.org
Since the early'60s, injections of a broad-spectrum muscarinic cholinergic agonist,
carbachol, into the medial pontine reticular formation (mPRF) of cats have been extensively …

Neuronal activity in the caudolateral peribrachial pons: relationship to PGO waves and rapid eye movements

S Datta, JA Hobson - Journal of Neurophysiology, 1994 - journals.physiology.org
1. The present study was performed to examine the hypothesis that the caudolateral
peribrachial area (C-PBL) may be directly involved in shifting the brain from the …

Physiological properties and afferent connections of the locus coeruleus and adjacent tegmental neurons involved in the generation of paradoxical sleep in the cat

K Sakai - Progress in brain research, 1991 - Elsevier
Results reported here confirm and extend those of early retrograde transport studies of the
brainstem in the rat and cat. This study demonstrates substantial and multiple afferent …

Central mechanisms of paradoxical sleep

K Sakai - Brain and Development, 1986 - Elsevier
Paradoxical sleep (PS) is composed of several characteristic “tonic” and “phasic” events. In
this paper, it was shown that each of these “PS-subsystems” might be generated by distinct …

Are there cholinergic and non-cholinergic paradoxical sleep-on neurones in the pons?

K Sakai, Y Koyama - Neuroreport, 1996 - journals.lww.com
USING microiontophoresis on unanesthetized head-restrained cats, we have found two
distinct groups of neurones exhibiting tonic discharge specific to paradoxical sleep (PS)(PS …

Cholinergic and noncholinergic brainstem neurons expressing Fos after paradoxical (REM) sleep deprivation and recovery

L Verret, L Léger, P Fort… - European Journal of …, 2005 - Wiley Online Library
It is well accepted that populations of neurons responsible for the onset and maintenance of
paradoxical sleep (PS) are restricted to the brainstem. To localize the structures involved …

c-fos Expression in mesopontine noradrenergic and cholinergic neurons of the cat during carbachol-induced active sleep: a double-labeling study.

J Yamuy, S Sampogna, FR Morales… - Sleep Research Online …, 1998 - europepmc.org
The interaction of cholinergic and catecholaminergic mechanisms in the mesopontine
region has been hypothesized as being critical for the generation and maintenance of active …

REM-enhancing effects of the adrenergic antagonist idazoxan infused into the medial pontine reticular formation of the freely moving cat

MJ Bier, RW McCarley - Brain Research, 1994 - Elsevier
Adrenergic input to the medial pontine reticular formation (mPRF) has been postulated to
play an important role in behavioral state control. Previous work has shown that direct …

Identification of cholinergic and non-cholinergic neurons in the pons expressing phosphorylated cyclic adenosine monophosphate response element-binding protein …

S Datta, DF Siwek, EC Stack - Neuroscience, 2009 - Elsevier
Recent studies have shown that in the pedunculopontine tegmental nucleus (PPT),
increased neuronal activity and kainate receptor-mediated activation of intracellular protein …