Epoxyeicosatrienoic acids (EETs) are released from endothelial cells and potently dilate
small arteries by hyperpolarizing vascular myocytes. In the present study, we investigated …

Epoxyeicosatrienoic acids (EETs) are metabolized by soluble epoxide hydrolase (sEH) to
form dihydroxyeicosatrienoic acids (DHETs) and are putative endothelium-derived …

1 Epoxyeicosatrienoic acids (EETs) have been described as endothelium‐derived hyper‐
polarizing factors (EDHFs), based on their stimulatory effects on smooth muscle K+ …

Epoxyeicosatrienoic acids (EETs) are endothelium-derived arachidonic acid metabolites of
cytochrome P450. They dilate coronary arteries, open K+ channels, and hyperpolarize …

Epoxyeicosatrienoic acids (EETs) cause vascular relaxation by activating smooth muscle
large conductance Ca2+-activated K+ (KCa) channels. EETs are metabolized to …

Cytochrome P450 epoxygenases convert arachidonic acid into 4 epoxyeicosatrienoic acid
(EET) regioisomers, which were recently identified as endothelium-derived hyperpolarizing …

Endothelium-dependent hyperpolarization and relaxation of vascular smooth muscle are
mediated by endothelium-derived hyperpolarizing factors (EDHFs). EDHF candidates …

1 Dihydroxyeicosatrienoic acids (DHETs), which are metabolites of arachidonic acid (AA)
and epoxyeicosatrienoic acids (EETs), have been identified as highly potent endogenous …

Diets enriched in docosahexaenoic acid, a major n-3 fatty acid in fish oil, have hypotensive
properties. One mechanism that can lower blood pressure is the direct dilation of arterioles …

Epoxyeicosatrienoic acids (EETs) are cytochrome P450–derived metabolites of arachidonic
acid. They are potent endogenous vasodilator compounds produced by vascular cells, and …