Aminergic and cholinergic afferents to REM sleep induction regions of the pontine reticular formation in the rat

K Semba - Journal of Comparative Neurology, 1993 - Wiley Online Library
Microinjection of cholinergic agonists in a dorsolateral part of the mesopontine tegmentum
has been shown to induce a rapid eye movement (REM) sleep‐like state. Physiological …

Electrical stimulation of the cholinergic laterodorsal tegmental nucleus elicits scopolamine-sensitive excitatory postsynaptic potentials in medial pontine reticular …

H Imon, K Ito, L Dauphin, RW McCarley - Neuroscience, 1996 - Elsevier
A large and consistent body of data implicates mesopontine cholinergic neurons in the
production of rapid eye movement sleep, and indicates that many rapid eye movement sleep …

Rapid eye movement sleep induction by microinjection of the GABA-A antagonist bicuculline into the dorsal subcoeruleus area of the rat

MS Pollock, RE Mistlberger - Brain research, 2003 - Elsevier
In cats, rapid eye movement sleep (REMS) can be induced rapidly and reliably by injections
of the cholinergic agonist carbachol into the anterodorsal pontine tegmentum, also …

Substance P in the descending cholinergic projection to REM sleep‐induction regions of the rat pontine reticular formation: anatomical and electrophysiological …

KA Kohlmeier, J Burns, PB Reiner… - European Journal of …, 2002 - Wiley Online Library
Release of acetylcholine within the pontine reticular formation (PRF) from the axon terminals
of mesopontine cholinergic neurons has long been hypothesized to play an important role in …

Regulation of rapid eye movement sleep in the freely moving rat: local microinjection of serotonin, norepinephrine, and adenosine into the brainstem

S Datta, V Mavanji, EH Patterson, J Ulloor - Sleep, 2003 - academic.oup.com
Abstract Study Objectives: Considerable evidence suggests that rapid eye movement (REM)
sleep is induced by glutamatergic activation of cholinergic cells within the pedunculopontine …

Role of dorsal raphe nucleus serotonin 5-HT1A receptor in the regulation of REM sleep

JM Monti, D Monti - Life sciences, 2000 - Elsevier
Cholinergic neurons in the laterodorsal (LDT) and the pedunculopontine (PPT) tegmental
nuclei act to promote REM sleep (REMS). The predominantly glutamatergic neurons of the …

Induction of rapid eye movement sleep by carbachol infusion into the pontine reticular formation in the rat

P Bourgin, P Escourrou, C Gaultier, J Adrien - Neuroreport, 1995 - journals.lww.com
CHOLINERGIC regulation of sleep and wakefulness was studied in freely moving rats
locally infused with various doses of carbachol into the pontine reticular formation. Induction …

Single cholinergic mesopontine tegmental neurons project to both the pontine reticular formation and the thalamus in the rat

K Semba, PB Reiner, HC Fibiger - Neuroscience, 1990 - Elsevier
Microinjections of the cholinergic agonist carbachol into a caudal part of the pontine reticular
formation of the rat induce a rapid eye movement sleep-like state. This carbachol-sensitive …

Serotonergic and cholinergic inhibition of mesopontine cholinergic neurons controlling REM sleep: an in vitro electrophysiological study

CS Leonard, R Llinas - Neuroscience, 1994 - Elsevier
Intracellular recordings were obtained from neurons of the laterodorsal tegmental and
pedunculopontine tegmental nuclei in a brain-slice preparation. The action of exogenously …

Carbachol microinjections in the mediodorsal pontine tegmentum are unable to induce paradoxical sleep after caudal pontine and prebulbar transections in the cat

G Vanni-Mercier, K Sakai, JS Lin, M Jouvet - Neuroscience letters, 1991 - Elsevier
In 7 cats, total transections of the brainstem at the caudal pontine or the prebulbar level led
to preparations which presented neither behavioral nor electrophysiological signs of …