Combined salmeterol and fluticasone in the treatment of chronic obstructive pulmonary disease: a randomised controlled trial

P Calverley, R Pauwels, J Vestbo, P Jones, N Pride… - The Lancet, 2003 - thelancet.com
Background Inhaled longacting β 2 agonists improve lung function and health status in
symptomatic chronic obstructive pulmonary disease (COPD), whereas inhaled …

Salmeterol and fluticasone propionate and survival in chronic obstructive pulmonary disease

PMA Calverley, JA Anderson, B Celli… - … England Journal of …, 2007 - Mass Medical Soc
Background Long-acting beta-agonists and inhaled corticosteroids are used to treat chronic
obstructive pulmonary disease (COPD), but their effect on survival is unknown. Methods We …

Effect of fluticasone with and without salmeterol on pulmonary outcomes in chronic obstructive pulmonary disease: a randomized trial

TS Lapperre, JB Snoeck-Stroband… - Annals of internal …, 2009 - acpjournals.org
Background: Inhaled corticosteroids (ICSs) and long-acting β2-agonists (LABAs) are used to
treat moderate to severe chronic obstructive pulmonary disease (COPD). Objective: To …

Impact of salmeterol/fluticasone propionate versus salmeterol on exacerbations in severe chronic obstructive pulmonary disease

P Kardos, M Wencker, T Glaab… - American journal of …, 2007 - atsjournals.org
Rationale: Exacerbations of chronic obstructive pulmonary disease (COPD) greatly
contribute to declining health status and the progression of the disease, thereby incurring …

Long-Acting β2 Agonists in the Management of Stable Chronic Obstructive Pulmonary Disease

M Cazzola, CF Donner - Drugs, 2000 - Springer
Long-acting β 2 agonist bronchodilators (eg formoterol, salmeterol) are a new interesting
therapeutic option for patients with chronic obstructive pulmonary disease (COPD). In the …

[HTML][HTML] Long-acting beta-agonists in the management of chronic obstructive pulmonary disease: current and future agents

DP Tashkin, LM Fabbri - Respiratory research, 2010 - Springer
Chronic obstructive pulmonary disease (COPD) is characterized by progressive airflow
limitation and debilitating symptoms. For patients with moderate-to-severe COPD, long …

Cardiovascular events in patients with COPD: TORCH study results

PMA Calverley, JA Anderson, B Celli, GT Ferguson… - Thorax, 2010 - thorax.bmj.com
Background Previous studies have suggested that long-term use of β agonists to treat
chronic obstructive pulmonary disease (COPD) may increase the risk of cardiovascular …

Survival in COPD patients after regular use of fluticasone propionate and salmeterol in general practice

JB Soriano, J Vestbo, NB Pride, V Kiri… - European …, 2002 - Eur Respiratory Soc
Despite substantial evidence regarding the benefits of combined use of inhaled
corticosteroids and long-acting β2-agonists in asthma, such evidence remains limited for …

Multicentre randomised placebo-controlled trial of inhaled fluticasone propionate in patients with chronic obstructive pulmonary disease

PL Paggiaro, R Dahle, I Bakran, L Frith, K Hollingworth… - The Lancet, 1998 - thelancet.com
Background The efficacy of inhaled corticosteroids in the treatment of chronic obstructive
pulmonary disease (COPD) remains controversial because of a lack of placebo-controlled …

Withdrawal of fluticasone propionate from combined salmeterol/fluticasone treatment in patients with COPD causes immediate and sustained disease deterioration: a …

EFM Wouters, DS Postma, B Fokkens, WCJ Hop… - Thorax, 2005 - thorax.bmj.com
Background: Guidelines recommend inhaled corticosteroids (ICS) as maintenance treatment
for patients with chronic obstructive pulmonary disease (COPD) with a post-bronchodilator …