Life-history trade-offs and the evolution of pathogen resistance: competition between host strains
The dynamics of a 'resistant'and a 'susceptible'strain of a self-regulated host species, in the
presence of a directly transmitted pathogen, is investigated. The two strains trade off …
presence of a directly transmitted pathogen, is investigated. The two strains trade off …
Decreased overall virulence in coinfected hosts leads to the persistence of virulent parasites
S Alizon - The American Naturalist, 2008 - journals.uchicago.edu
Multiple infections are known to affect virulence evolution. Some studies even show that
coinfections may decrease the overall virulence (the disease-induced mortality of a …
coinfections may decrease the overall virulence (the disease-induced mortality of a …
Complex dynamic behaviours in the interaction between parasite populations and the host's immune system
RM Anderson - International Journal for Parasitology, 1998 - Elsevier
The paper describes recent progress in the development of a mathematical framework for
the study of the epidemiology, evolution, within-host parasite population growth and the …
the study of the epidemiology, evolution, within-host parasite population growth and the …
The curse of the pharaoh: the evolution of virulence in pathogens with long living propagules
S Bonhoeffer, RE Lenski… - Proceedings of the …, 1996 - royalsocietypublishing.org
We used a mathematical model to evaluate the hypothesis that parasites and pathogens
with long living propagules should evolve high levels of virulence, ie high rates of pathogen …
with long living propagules should evolve high levels of virulence, ie high rates of pathogen …
Periodic host absence can select for higher or lower parasite transmission rates
F van den Berg, N Bacaer, JAJ Metz, C Lannou… - Evolutionary …, 2011 - Springer
This paper explores the effect of discontinuous periodic host absence on the evolution of
pathogen transmission rates by using R 0 maximisation techniques. The physiological …
pathogen transmission rates by using R 0 maximisation techniques. The physiological …
The concept of virulence: interpretations and implications
R Poulin, C Combes - Parasitology Today, 1999 - cell.com
The word 'virulence'has the same Latin origin as the word 'virus', which originally refered to
any pathogen that caused disease. Virulence should therefore refer specifically to a property …
any pathogen that caused disease. Virulence should therefore refer specifically to a property …
Evolution of pathogen virulence: the role of variation in host phenotype
KS Pfennig - Proceedings of the Royal Society of London …, 2001 - royalsocietypublishing.org
Selection on pathogens tends to favour the evolution of growth and reproductive rates and a
concomitant level of virulence (damage done to the host) that maximizes pathogen fitness …
concomitant level of virulence (damage done to the host) that maximizes pathogen fitness …
The epidemiological consequences of optimisation of the individual host immune response
GF Medley - Parasitology, 2002 - cambridge.org
We present a simple unscaled, quantitative framework that addresses the optimum use of
resources throughout a host's lifetime based on continuous exposure to parasites (rather …
resources throughout a host's lifetime based on continuous exposure to parasites (rather …
Coevolutionary theory of hosts and parasites
LJ Buckingham, B Ashby - Journal of Evolutionary Biology, 2022 - academic.oup.com
Host and parasite evolution are closely intertwined, with selection for adaptations and
counter‐adaptations forming a coevolutionary feedback loop. Coevolutionary dynamics are …
counter‐adaptations forming a coevolutionary feedback loop. Coevolutionary dynamics are …
Kin selection and virulence in the evolution of protocells and parasites
SA Frank - Proceedings of the Royal Society of London …, 1994 - royalsocietypublishing.org
The evolution of parasite virulence and the origin of cooperative genomes in primitive cells
are both problems that balance cooperative and competitive interactions among symbionts. I …
are both problems that balance cooperative and competitive interactions among symbionts. I …