Coinfection and the evolution of parasite virulence

RM May, MA Nowak - … of the Royal Society of London …, 1995 - royalsocietypublishing.org
Analyses of the selection pressures acting on parasite virulence are made more complicated
when individual hosts can simultaneously harbour many different strains or genotypes of a …

Superinfection and the evolution of parasite virulence

MA Nowak, RM May - … of the Royal Society of London …, 1994 - royalsocietypublishing.org
Earlier ideas that parasites evolve toward becoming harmless to their hosts have, in recent
years, given way to more analytic studies, focused on the 'basic reproductive rate', R o, of …

Does multiple infection select for raised virulence?

SP Brown, ME Hochberg, BT Grenfell - Trends in microbiology, 2002 - cell.com
Classical models of virulence evolution conclude that the increased competition favoured by
multiple infection will select for increasing consumption and deterioration of the host …

Evolution of virulence in a heterogeneous host population

RR Regoes, MA Nowak, S Bonhoeffer - Evolution, 2000 - Wiley Online Library
There is a large body of theoretical studies that investigate factors that affect the evolution of
virulence, that is parasite‐induced host mortality. In these studies the host population is …

Host life history and the evolution of parasite virulence

S Gandon, VAA Jansen, M Van Baalen - Evolution, 2001 - academic.oup.com
Abstract.—We present a general epidemiological model of host‐parasite interactions that
includes various forms of superinfection. We use this model to study the effects of different …

Parasite and host assemblages: embracing the reality will improve our knowledge of parasite transmission and virulence

T Rigaud, MJ Perrot-Minnot… - Proceedings of the …, 2010 - royalsocietypublishing.org
Interactions involving several parasite species (multi-parasitized hosts) or several host
species (multi-host parasites) are the rule in nature. Only a few studies have investigated …

Evolution of virulence: a unified framework for coinfection and superinfection

J Mosquera, FR Adler - Journal of Theoretical Biology, 1998 - Elsevier
Models of the evolution of parasite virulence have focused on computing the evolutionarily
stable level of virulence favored by tradeoffs within a host and by competition for hosts, and …

Mutation and the evolution of virulence

S Bonhoeffer, MA Nowak - Proceedings of the Royal …, 1994 - royalsocietypublishing.org
The evolution of parasite virulence can be influenced by intra-host mutation of the parasite
and competition among different parasite mutants in the same host. During the course of an …

The evolution of virulence in parasites and pathogens: reconciliation between two competing hypotheses

RE Lenski, RM May - Journal of theoretical biology, 1994 - Elsevier
According to conventional wisdom, parasites and pathogens should evolve reduced
virulence to their hosts, because more virulent parasites and pathogens are more likely to …

Virulence

JJ Bull - Evolution, 1994 - Wiley Online Library
Why do parasites harm their hosts? Intuition suggests that parasites should evolve to be
benign whenever the host is needed for transmission. Yet a growing theoretical literature …