Comparative Genomics of Serial Isolates of Cryptococcus neoformans Reveals Gene Associated With Carbon Utilization and Virulence

KL Ormerod, CA Morrow, EWL Chow… - G3: Genes …, 2013 - academic.oup.com
The opportunistic fungal pathogen Cryptococcus neoformans is a leading cause of mortality
among the human immunodeficiency virus/acquired immunodeficiency syndrome …

Deciphering the Model Pathogenic Fungus Cryptococcus Neoformans

A Idnurm, YS Bahn, K Nielsen, X Lin… - Nature Reviews …, 2005 - nature.com
Cryptococcus neoformans is a basidiomycete fungal pathogen of humans that has diverged
considerably from other model fungi such as Neurospora crassa, Aspergillus nidulans …

What makes Cryptococcus neoformans a pathogen?

KL Buchanan, JW Murphy - Emerging infectious diseases, 1998 - ncbi.nlm.nih.gov
Life-threatening infections caused by the encapsulated fungal pathogen Cryptococcus
neoformans have been increasing steadily over the past 10 years because of the onset of …

Cryptococcus neoformans, a global threat to human health

Y Zhao, L Ye, F Zhao, L Zhang, Z Lu, T Chu… - Infectious Diseases of …, 2023 - mednexus.org
Background Emerging fungal pathogens pose important threats to global public health. The
World Health Organization has responded to the rising threat of traditionally neglected …

Surface-Associated Plasminogen Binding of Cryptococcus neoformans Promotes Extracellular Matrix Invasion

J Stie, G Bruni, D Fox - PloS one, 2009 - journals.plos.org
Background The fungal pathogen Cryptococcus neoformans is a leading cause of illness
and death in persons with predisposing factors, including: malignancies, solid organ …

Microevolution of a Standard Strain ofCryptococcus neoformans Resulting in Differences in Virulence and Other Phenotypes

SP Franzot, J Mukherjee, R Cherniak… - Infection and …, 1998 - Am Soc Microbiol
Cryptococcus neoformans is a major fungal pathogen for patients with debilitated immune
systems. However, no information is available on the stability of virulence or of phenotypes …

Enhanced Innate Immune Responsiveness to Pulmonary Cryptococcus neoformans Infection Is Associated with Resistance to Progressive Infection

L Guillot, SF Carroll, R Homer… - Infection and immunity, 2008 - Am Soc Microbiol
Genetically regulated mechanisms of host defense against Cryptococcus neoformans
infection are not well understood. In this study, pulmonary infection with the moderately …

Cryptococcus neoformans Infection in the Central Nervous System: The Battle between Host and Pathogen

Y Chen, ZW Shi, AB Strickland, M Shi - Journal of Fungi, 2022 - mdpi.com
Cryptococcus neoformans (C. neoformans) is a pathogenic fungus with a global distribution.
Humans become infected by inhaling the fungus from the environment, and the fungus …

Role of Phagocytosis in the Virulence of Cryptococcus neoformans

M Del Poeta - Eukaryotic cell, 2004 - Am Soc Microbiol
Phagocytosis is a receptor-mediated process that leads to the internalization of foreign
particles into phagocytic cells. Phagocytic cells, such as macrophages, dendritic cells, and …

Mixed Infections and In Vivo Evolution in the Human Fungal Pathogen Cryptococcus neoformans

M Desnos-Ollivier, S Patel, AR Spaulding, C Charlier… - MBio, 2010 - Am Soc Microbiol
Koch's postulates are criteria establishing a causal relationship between a microbe and a
disease that lead to the assumption that diseases are caused by a single strain or its …