Coexistence of gonadotrophin‐releasing hormone and Galanin: Immunohisto‐chemical and functional studies

CW Coen, C Montagnese… - Journal of …, 1990 - Wiley Online Library
Our observation of galanin‐immunoreactive perikarya with morphological characteristics
strikingly similar to those containing gorvadotrophin‐releasmg hormone (GnRH) led us to …

Galanin: a hypothalamic-hypophysiotropic hormone modulating reproductive functions.

FJ Lopez, I Merchenthaler, M Ching… - Proceedings of the …, 1991 - National Acad Sciences
Galanin (GAL) is widely distributed in the peripheral and the central nervous systems. In the
brain, the highest GAL concentrations are observed within the hypothalamus and …

Regulation of galanin gene expression in gonadotropin-releasing hormone neurons during the estrous cycle of the rat

DL Marks, MS Smith, M Vrontakis, DK Clifton… - …, 1993 - academic.oup.com
Galanin is colocalized with GnRH in neurons of the hypothalamus and basal forebrain of
female rats, and this neuropeptide may play a role in the generation of the midcycle surge of …

Evidence for expression of galanin receptor Gal‐R1 mRNA in certain gonadotropin releasing hormone neurones of the rostral preoptic area

Bouret, Prévot, Jennes… - Journal of …, 1999 - Wiley Online Library
Previous studies have shown that galanin plays an important role in the regulation of
gonadotropin releasing hormone (GnRH) release. At present, it is not known if this role is …

Endogenous galanin modulates the gonadotropin and prolactin proestrous surges in the rat

FJ Lopez, EH Meade Jr, A Negro-Vilar - Endocrinology, 1993 - academic.oup.com
Galanin (GAL) has recently emerged as an important neuroendocrine regulator which
participates in the control of several pituitary and hypothalamic hormones. Our earlier …

Regulation of gonadotropin-releasing hormone (GnRH) and galanin gene expression in GnRH neurons during lactation in the rat

DL Marks, MS Smith, DK Clifton, RA Steiner - Endocrinology, 1993 - academic.oup.com
Galanin is colocalized with GnRH, and its expression in these neurons is enhanced at
proestrus, a time of activation of GnRH neurons. We tested the hypothesis that the …

Expression of galanin immunoreactivity in gonadotropin-releasing hormone neurons in mice: a confocal microscopic study

G Rajendren, MJ Gibson - Brain research, 1999 - Elsevier
The expression of galanin immunoreactivity (galanin-IR) in gonadotropin-releasing hormone
(GnRH) neurons was investigated in mice using double label immunohistochemistry …

Colocalization of galanin and luteinizing hormone-releasing hormone in a subset of preoptic hypothalamic neurons: anatomical and functional correlates.

I Merchenthaler, FJ Lopez… - Proceedings of the …, 1990 - National Acad Sciences
Colocalization of neurotransmitters, including neuropeptides and amines, in the same
neuron of certain areas or well-defined nuclei of the central and peripheral nervous systems …

Galanin is a paracrine inhibitor of gonadotroph function in the female rat

JF Todd, CJ Small, KO Akinsanya, SA Stanley… - …, 1998 - academic.oup.com
Recent evidence suggests that pituitary galanin synthesized in the lactotroph is a paracrine
regulator of lactotroph proliferation and PRL secretion and that these effects are mediated …

Galanin enhancement of gonadotropin-releasing hormone-stimulated luteinizing hormone secretion in female rats is estrogen dependent

CL Splett, JR Scheffen, JA Desotelle, V Plamann… - …, 2003 - academic.oup.com
The hypothalamic peptide GnRH is the primary neuroendocrine signal regulating pituitary
LH in females. The neuropeptide galanin is cosecreted with GnRH from hypothalamic …