Background COPD exacerbations are responsible for the morbidity and mortality of this
disease. The relationship between exacerbations and patient-related clinical outcomes is …

Background Exacerbations affect morbidity in chronic obstructive pulmonary disease
(COPD). We sought to evaluate the association between exacerbation frequency and …

Background Exacerbation frequency is related to disease progression, quality of life, and
prognosis in COPD. Earlier diagnosis, along with interventions aimed at preventing …

Background COPD exacerbations are associated with accelerated lung function decline, but
whether they are causal is unknown. We evaluated the effect of a single exacerbation on …

Background Data examining the characteristics of patients with frequent exacerbations of
chronic obstructive pulmonary disease (COPD) and associated hospitalisations and …

COPD is associated with significant morbidity and is one of the leading causes of death
worldwide. Periods of exacerbation, the acute worsening of symptoms, are interspersed …

Introduction Chronic obstructive pulmonary disease (COPD) exacerbations are associated
with systemic consequences. Data from a 4-year trial (Understanding Potential Long-term …

Exacerbations of chronic obstuctive pulmonary disease (COPD) are associated with worse
health status. The Inhaled Steroids in Obstructive Lung Disease in Europe (ISOLDE) study …

Objective: The ability to predict exacerbations in patients with COPD might permit more
rational use of preventive interventions. Our objective was to develop risk indexes for …

Background Acute exacerbations may cause deteriorations in the health status of subjects
with chronic obstructive pulmonary disease (COPD). The present study prospectively …