Antidepressant medications are typically taken on a daily basis owing to both tradition and
the pharmacokinetics of these agents. Because fluoxetine and its primary metabolite …

Elderly patients commonly receive statin drugs for the primary or secondary prevention of
cardiovascular and cerebrovascular events. Elderly patients also commonly receive …

Background: Severity of anxiety does not appear to influence the antidepressant response to
fluoxetine during acute treatment of major depressive disorder (MDD). We report a …

Sir: In patients with bipolar I disorder, low total serum cholesterol levels have been reported
during full remission and manic and depressive episodes. 1, 2 Several cohort studies 3-5 …

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Discussion The course of this patient's problems could be explained by a series of adverse
drug-drug interactions. The patient's catatonia could be due to an adverse drug-drug …

Background: Major depressive disorder (MDD) is associated with significant disability,
having a profound impact on psychosocial functioning. Therefore, studying the impact of …

Objective: Although continuing antidepressant treatment after patients have responded to
medication has been shown to greatly reduce the risk of relapse, this risk is not eliminated. A …

Some patients relapse while taking previously effective doses of selective serotonin
reuptake inhibitor antidepressants (SSRI), as they do with other antidepressants.[1-4] …

Background: In spite of impressive results in acute studies, the long-term treatment of major
depression remains problematic. To explore the return of depressive symptoms and their …