Venlafaxine (VFX) is a novel nontricyclic antidepressant that inhibits neuronal uptake of
serotonin, noradrenaline, and dopamine in order of decreasing potency. 1 Unlike tricyclic …

To the Editor: Selective serotonin reuptake inhibiting antidepressants (SSRIs) commonly
produce iatrogenic sexual dysfunction (1, 2). Spontaneous remission of SSRI-induced …

Background: A subset of patients experience worsening of depressed mood after beginning
antidepressant treatment, which could represent the natural history of the illness or a …

Background: We assessed the tolerability and utility of switching fluoxetine nonresponders
to citalopram the day that fluoxetine therapy was stopped. Method: Fifty-eight outpatients …

TO THE EDITOR: Lamotrigine, which at present has been indicated only for the treatment of
epilepsy, has been reported to be possibly useful as an adjunctive treatment for bipolar …

BACKGROUND: Data about follow-up after acute pharmacological treatment of psychotic
depression are scarce. METHODS: A 4month open follow-up was done, preferentially with …

Selective serotonin reuptake inhibitors (SSRIs) are a class of medications whose primary
mechanism of action is via antagonism of the 5-HT transporter, which results in the inhibition …

Recurrent unipolar depression is a common, but undertreated disorder. Many patients
require long-term maintenance therapy, and full doses of antidepressant agents may be …

DISCUSSION As its main finding, the present longitudinal study reveals an improvement of
ISI Stumvoll 8 in nondiabetic depressed patients only after remission to antidepressive …

The good news is that advances in the treatment of depression in the past decade have led
to better recognition of those with depression, and also to a reduction in the number of …