Background COPD exacerbations are associated with accelerated lung function decline, but
whether they are causal is unknown. We evaluated the effect of a single exacerbation on …

Background Exacerbations affect morbidity in chronic obstructive pulmonary disease
(COPD). We sought to evaluate the association between exacerbation frequency and …

Background COPD exacerbations are responsible for the morbidity and mortality of this
disease. The relationship between exacerbations and patient-related clinical outcomes is …

Background Exacerbations of chronic obstructive pulmonary disease (COPD) are
associated with loss of lung function and poor outcomes for patients. However, there are …

AIM: To investigate whether there is a significant relationship between an increased
frequency of exacerbations and the rate of forced expiratory volume in 1s (FEV1) decline in …

Background: Chronic obstructive pulmonary disease (COPD) is characterised by both an
accelerated decline in lung function and periods of acute deterioration in symptoms termed …

Introduction Chronic obstructive pulmonary disease (COPD) exacerbations are associated
with systemic consequences. Data from a 4-year trial (Understanding Potential Long-term …

Purpose To quantify the relationship between severity of chronic obstructive pulmonary
disease (COPD) as expressed by Global Initiative for Chronic Obstructive Lung Disease …

Exacerbations are an important feature and outcome measure in chronic obstructive
pulmonary disease (COPD), but little is known about changes in their severity, recovery …

Background Exacerbation history is used to grade the risk of COPD exacerbation, but its
reliability and relationship to other risk factors and prior therapy is unclear. To examine these …