Effect of exacerbations on quality of life in patients with chronic obstructive pulmonary disease: a 2 year follow up study

M Miravitlles, M Ferrer, A Pont, R Zalacain… - Thorax, 2004 - thorax.bmj.com
Background: A study was undertaken to evaluate exacerbations and their impact on the
health related quality of life (HRQL) of patients with chronic obstructive pulmonary disease …

Clinical features and determinants of COPD exacerbation in the Hokkaido COPD cohort study

M Suzuki, H Makita, YM Ito, K Nagai… - European …, 2014 - Eur Respiratory Soc
Exacerbations are among the major factors that may affect the natural history of chronic
obstructive pulmonary disease (COPD). The aim was to investigate the clinical …

Withdrawal from treatment as an outcome in the ISOLDE study of COPD

PMA Calverley, S Spencer, L Willits, PS Burge… - Chest, 2003 - Elsevier
Objectives To investigate the determinants of patient withdrawal from our study, and the
effect of these withdrawals on the outcome of treatment with inhaled corticosteroids in …

[HTML][HTML] Impact of hospitalisations for exacerbations of COPD on health-related quality of life

C Esteban, JM Quintana, J Moraza, M Aburto… - Respiratory …, 2009 - Elsevier
Exacerbations of chronic obstructive pulmonary disease (COPD) impair health-related
quality of life (HRQoL). It is unknown whether exacerbations requiring hospitalisation have …

Association between lung function and exacerbation frequency in patients with COPD

M Hoogendoorn, TL Feenstra… - … journal of chronic …, 2010 - Taylor & Francis
Purpose To quantify the relationship between severity of chronic obstructive pulmonary
disease (COPD) as expressed by Global Initiative for Chronic Obstructive Lung Disease …

Statistical analysis of exacerbation rates in COPD: TRISTAN and ISOLDE revisited

ON Keene, PMA Calverley, PW Jones… - European …, 2008 - Eur Respiratory Soc
Various statistical methods have been used to measure the impact of treatment on chronic
obstructive pulmonary disease (COPD) exacerbations. Poisson regression has recently …

Randomised, double blind, placebo controlled study of fluticasone propionate in patients with moderate to severe chronic obstructive pulmonary disease: the ISOLDE …

PS Burge, PMA Calverley, PW Jones, S Spencer… - Bmj, 2000 - bmj.com
Objectives: To determine the effect of long term inhaled corticosteroids on lung function,
exacerbations, and health status in patients with moderate to severe chronic obstructive …

Acute exacerbation of COPD

FW Ko, KP Chan, DS Hui, JR Goddard, JG Shaw… - …, 2016 - Wiley Online Library
The literature of acute exacerbation of chronic obstructive pulmonary disease (COPD) is fast
expanding. This review focuses on several aspects of acute exacerbation of COPD …

The acute COPD exacerbation prediction tool (ACCEPT): a modelling study

A Adibi, DD Sin, A Safari, KM Johnson… - The Lancet …, 2020 - thelancet.com
Background Accurate prediction of exacerbation risk enables personalised care for patients
with chronic obstructive pulmonary disease (COPD). We developed and validated a …

Association between COPD exacerbations and lung function decline during maintenance therapy

M Kerkhof, J Voorham, P Dorinsky, C Cabrera… - Thorax, 2020 - thorax.bmj.com
Background Little is known about the impact of exacerbations on COPD progression or
whether inhaled corticosteroid (ICS) use and blood eosinophil count (BEC) affect …