We investigated the impact of season relative to other determinants of chronic obstructive
pulmonary disease (COPD) exacerbation frequency in a long-term international study of …

There is little information available concerning the extent to which chronic obstructive
pulmonarv disease (COPD) patients are satisfactorily managed, especially, regards factors …

BACKGROUND The role of inhaled corticosteroids in the long term management of chronic
obstructive pulmonary disease (COPD) is still unclear. A meta-analysis of the original data …

Exacerbations occur commonly in patients with moderate or severe chronic obstructive
pulmonary disease (COPD) but factors affecting their severity and frequency or effects on …

Background The widespread use of inhaled corticosteroids (ICSs) for COPD treatment has
been questioned. Recent studies of weaning some patients with COPD off ICSs found little …

Exacerbations of chronic obstructive pulmonary disease (COPD) are defined as sustained
worsening of a patient's condition beyond normal day-to-day variations that is acute in onset …

Background Inhaled corticosteroids (ICS) have been shown to decrease the occurrence of
COPD exacerbations. However, the relationship of baseline lung function and reduction of …

Background: Clinical trials measure exacerbations of chronic obstructive pulmonary disease
(COPD) inconsistently. A study was undertaken to determine if different methods for …

The high prevalence and chronicity of chronic obstructive pulmonary disease (COPD) imply
that many of these patients are treated and controlled in primary-care centres, often without …

Background: A trial of corticosteroids has been recommended for all patients with chronic
obstructive pulmonary disease (COPD), with the subsequent “response” determining the …