Withdrawal of fluticasone propionate from combined salmeterol/fluticasone treatment in patients with COPD causes immediate and sustained disease deterioration: a …

EFM Wouters, DS Postma, B Fokkens, WCJ Hop… - Thorax, 2005 - thorax.bmj.com
Background: Guidelines recommend inhaled corticosteroids (ICS) as maintenance treatment
for patients with chronic obstructive pulmonary disease (COPD) with a post-bronchodilator …

Effect of fluticasone propionate/salmeterol (250/50) on COPD exacerbations and impact on patient outcomes

A Anzueto, GT Ferguson, G Feldman… - COPD: Journal of …, 2009 - Taylor & Francis
Prevention and treatment of COPD exacerbations are recognized as key goals in disease
management. This randomized, double-blind, parallel-group, multicenter study evaluated …

Salmeterol & Fluticasone 50 μg/250 μg bid in combination provides a better long-term control than salmeterol 50 μg bid alone and placebo in COPD patients already …

RW Dal Negro, C Pomari, S Tognella… - Pulmonary pharmacology …, 2003 - Elsevier
Bronchodilator agents are central to the symptomatic management of Chronic Obstructive
Pulmonary Disease (COPD), and long-acting inhaled bronchodilators are regarded as more …

Early onset of effect of salmeterol and fluticasone propionate in chronic obstructive pulmonary disease

J Vestbo, R Pauwels, JA Anderson, P Jones… - Thorax, 2005 - thorax.bmj.com
Background: Combined treatment with inhaled corticosteroids and long acting β2 agonists is
approved for the treatment of chronic obstructive pulmonary disease (COPD), but little is …

[HTML][HTML] Effect of fluticasone propionate/salmeterol (250/50 μg) or salmeterol (50 μg) on COPD exacerbations

GT Ferguson, A Anzueto, R Fei, A Emmett, K Knobil… - Respiratory …, 2008 - Elsevier
OBJECTIVES: COPD exacerbations are associated with significant morbidity and mortality.
This randomized, double-blind, parallel-group, multicenter study evaluated the effect of …

Survival in COPD patients after regular use of fluticasone propionate and salmeterol in general practice

JB Soriano, J Vestbo, NB Pride, V Kiri… - European …, 2002 - Eur Respiratory Soc
Despite substantial evidence regarding the benefits of combined use of inhaled
corticosteroids and long-acting β2-agonists in asthma, such evidence remains limited for …

Disease severity and the effect of fluticasone propionate on chronic obstructive pulmonary disease exacerbations

PW Jones, LR Willits, PS Burge… - European Respiratory …, 2003 - Eur Respiratory Soc
Exacerbations of chronic obstructive pulmonary disease (COPD) are associated with worse
health and increased healthcare utilisation. The Inhaled Steroids in Obstructive Lung …

Effect of fluticasone with and without salmeterol on pulmonary outcomes in chronic obstructive pulmonary disease: a randomized trial

TS Lapperre, JB Snoeck-Stroband… - Annals of internal …, 2009 - acpjournals.org
Background: Inhaled corticosteroids (ICSs) and long-acting β2-agonists (LABAs) are used to
treat moderate to severe chronic obstructive pulmonary disease (COPD). Objective: To …

Withdrawal from treatment as an outcome in the ISOLDE study of COPD

PMA Calverley, S Spencer, L Willits, PS Burge… - Chest, 2003 - Elsevier
Objectives To investigate the determinants of patient withdrawal from our study, and the
effect of these withdrawals on the outcome of treatment with inhaled corticosteroids in …

Effectiveness of fluticasone furoate–vilanterol for COPD in clinical practice

J Vestbo, D Leather, N Diar Bakerly… - … England Journal of …, 2016 - Mass Medical Soc
Background Evidence for the management of chronic obstructive pulmonary disease
(COPD) comes from closely monitored efficacy trials involving groups of patients who were …