The chicken B locus is a minimal essential major histocompatibility complex

J Kaufman, S Milne, TWF Göbel, BA Walker, JP Jacob… - Nature, 1999 - nature.com
Here we report the sequence of the region that determines rapid allograft rejection in
chickens, the chicken major histocompatibility complex (MHC). This 92-kilobase region of …

The simple chicken major histocompatibility complex: life and death in the face of pathogens and vaccines

J Kaufman - … Transactions of the Royal Society of …, 2000 - royalsocietypublishing.org
In contrast to the major histocompatibility complex (MHC) of well-studied mammals such as
humans and mice, the particular haplotype of the BF/BL region of the chicken B locus …

Gene organisation determines evolution of function in the chicken MHC

J Kaufman, J Jacob, J Shaw, B Walker… - Immunological …, 1999 - Wiley Online Library
Some years ago, we used our data for class I genes, proteins and peptide‐binding
specificities to develop the hypothesis that the chicken B‐F/B‐L region represents a “minimal …

Different evolutionary histories of the two classical class I genes BF1 and BF2 illustrate drift and selection within the stable MHC haplotypes of chickens

I Shaw, TJ Powell, DA Marston, K Baker… - The Journal of …, 2007 - journals.aai.org
Compared with the MHC of typical mammals, the chicken MHC (BF/BL region) of the B12
haplotype is smaller, simpler, and rearranged, with two classical class I genes of which only …

Concerted evolution of two Mhc class II B loci in pheasants and domestic chickens.

H Wittzell, A Bernot, C Auffray… - Molecular Biology and …, 1999 - academic.oup.com
The major histocompatibility complex (Mhc) of the ring-necked pheasant contains two
polymorphic Mhc class II B genes. We show here, by screening of a cDNA library and RT …

A three-locus model for the chicken major histocompatibility complex

JRL Pink, W Droege, K Hala, VC Miggiano, A Ziegler - Immunogenetics, 1977 - Springer
The major histocompatibility complexes (B complexes) of chickens of various origins have
been studied by serological and biochemical methods. Two B complexes are of particular …

Nomenclature for chicken major histocompatibility (B) complex.

WE Briles, N Bumstead, DL Ewert, DG Gilmour… - 1982 - cabidigitallibrary.org
A workshop was held held at the Institute for General and Experimental Pathology,
University of Innsbruck Medical School, Austria, 9-11 Sep. 1981, to compare the MHC …

Structures of an MHC class I molecule from B21 chickens illustrate promiscuous peptide binding

M Koch, S Camp, T Collen, D Avila, J Salomonsen… - Immunity, 2007 - cell.com
Little is known about the structure of major histocompatibility complex (MHC) molecules
outside of mammals. Only one class I molecule in the chicken MHC is highly expressed …

The “minimal essential MHC” revisited: both peptide‐binding and cell surface expression level of MHC molecules are polymorphisms selected by pathogens in …

J Kaufman, J Salomonsen - Hereditas, 1997 - Wiley Online Library
Birds, like mammals, have a highly polymorphic MHC that determines strong allograft
rejection. However, in contrast to mammals, there are a number of viral diseases for which …

Resistance to a Malignant Lymphoma in Chickens Is Mapped to Subregion of Major Histocompatibility (B) Complex

WE Briles, RW Briles, RE Taffs, HA Stone - Science, 1983 - science.org
A genetic recombinant within the major histocompatibility (B) complex of the chicken has
revealed the chromosomal subregion effecting resistance to Marek's disease—a malignant …