Abstract Chicken beta 2-microglobulin (beta 2m) and class I (B-F19 alpha chain) cDNA
clones were isolated and the sequences compared to those of BF Ag isolated from chicken …

Background Due to its high polymorphism and importance for disease resistance, the major
histocompatibility complex (MHC) has been an important focus of many vertebrate genome …

The influence of major histocompatibility complex (MHC) gene products on the T-lymphocyte
αβ receptor (TCR) repertoire is well documented1–4, but how specificity is also generated …

The major histocompatibility complex (MHC) is a multigene complex of tightly linked
homologous genes that encode cell surface antigens that play a key role in immune …

The class I genes of the major histocompatibility complex (Mhc) are here investigated for the
first time in a passerine bird. The great reed warbler is a rare species in Sweden with a few …

In the evolution of the adaptive immune system unique to vertebrates, teleost fish occupy the
critical position. This is the most primitive class of lower vertebrates in which the capacity for …

WE describe a mutant human cell line (LBL 721.174) 1, 2 that has lost a function required for
presentation of intracellular viral antigens with class I molecules of the major …

This review of the RT1 complex, the major histocompatibility complex (MHC) of the rat,
focuses on genetic, genomic, evolutionary, and functional aspects at the molecular level …

THE structure of HLA substances make it surprising that they provoke strong alloimmune
responses1–3. They are composed of two chains, one invariant within the species, and the …

Butcher and their colleagues, who have independently identified the rat homologues of the
HAM genes and associate expression of these genes with differences in conformation and …