Relationship between respiratory symptoms and medical treatment in exacerbations of COPD

P Calverley, R Pauwels, CG Löfdahl… - European …, 2005 - Eur Respiratory Soc
Exacerbations of chronic obstructive pulmonary disease (COPD) can be defined
symptomatically or by healthcare contacts, yet the relationship between these events is …

Time course and pattern of COPD exacerbation onset

SD Aaron, GC Donaldson, GA Whitmore, JR Hurst… - Thorax, 2012 - thorax.bmj.com
Background The natural history and time course of the onset of exacerbation events of
chronic obstructive pulmonary disease (COPD) is incompletely understood. Methods A …

Impact on patients' health status following early identification of a COPD exacerbation

J Bourbeau, G Ford, H Zackon, N Pinsky… - European …, 2007 - Eur Respiratory Soc
The current study aimed to assess the impact on patient health status during an acute
exacerbation of chronic obstructive pulmonary disease (AECOPD). A total of 421 COPD …

[HTML][HTML] Prediction and course of symptoms and lung function around an exacerbation in chronic obstructive pulmonary disease

M Van Den Berge, WCJ Hop, T van der Molen… - Respiratory …, 2012 - Springer
Background Frequent exacerbations induce a high burden to Chronic Obstructive
Pulmonary Disease (COPD). We investigated the course of exacerbations in the published …

Predictive accuracy of patient-reported exacerbation frequency in COPD

JK Quint, GC Donaldson, JR Hurst… - European …, 2011 - Eur Respiratory Soc
Chronic obstructive pulmonary disease (COPD) exacerbation frequency is important for
clinical risk assessment and trial recruitment. In order to accurately establish exacerbation …

Longitudinal changes in the nature, severity and frequency of COPD exacerbations

GC Donaldson, TAR Seemungal… - European …, 2003 - Eur Respiratory Soc
Exacerbations are an important feature and outcome measure in chronic obstructive
pulmonary disease (COPD), but little is known about changes in their severity, recovery …

[HTML][HTML] Factors associated with change in exacerbation frequency in COPD

GC Donaldson, H Müllerova, N Locantore, JR Hurst… - Respiratory …, 2013 - Springer
Background Patients with chronic obstructive pulmonary disease (COPD) can be
categorized as having frequent (FE) or infrequent (IE) exacerbations depending on whether …

Characterizing and quantifying the symptomatic features of COPD exacerbations

PW Jones, WH Chen, TK Wilcox, S Sethi, NK Leidy… - Chest, 2011 - Elsevier
Background There is a need for a standardized, valid, and reliable instrument for quantifying
exacerbations of COPD. The objective of this study was to identify symptom items that …

A score to predict short-term risk of COPD exacerbations (SCOPEX)

BJ Make, G Eriksson, PM Calverley… - … journal of chronic …, 2015 - Taylor & Francis
Background There is no clinically useful score to predict chronic obstructive pulmonary
disease (COPD) exacerbations. We aimed to derive this by analyzing data from three …

[HTML][HTML] Patients' experience of identifying and managing exacerbations in COPD: a qualitative study

V Williams, M Hardinge, S Ryan… - NPJ primary care …, 2014 - nature.com
Background: Effective self-management in chronic obstructive pulmonary disease (COPD) is
crucial to reduce hospital admissions and improve outcomes for patients. This includes early …