[HTML][HTML] Total plasma homocysteine measurement: Evaluation of the Abbott immunoassay, comparison with the JEOL ion exchange chromatography and investigation …

KFK Suen, GR Lee, M Finnegan, K Halton… - Practical Laboratory …, 2022 - Elsevier
Objectives Homocysteine is an intermediary amino acid formed in methionine metabolism,
with elevated total homocysteine (tHCY) being a biomarker of cardiovascular and …

Simultaneous determination of plasma total homocysteine and methionine by liquid chromatography-tandem mass spectrometry

Y Jiang, B Mistretta, S Elsea, Q Sun - Clinica Chimica Acta, 2017 - Elsevier
The sulfur-containing amino acid homocysteine is a cardiac risk factor and a biomarker for
several inborn errors of metabolism in methionine synthesis. A simple LC-MS/MS method …

Liquid chromatographic assessment of total and protein-bound homocysteine in human plasma

E Bald, E Kaniowska, G Chwatko, R Glowacki - Talanta, 2000 - Elsevier
Homocysteine present in human blood plasma is derivatized with thiol selective ultraviolet
labelling reagent, 2-chloro-1-methylpyridinium iodide, and separated from other plasma thiol …

Low diagnostic value of fasting and post-methionine load homocysteine tests. A study in Dutch subjects with homocysteine test indications

MR Fokkema, DAJ Dijck-Brouwer, JJ van Doormaal… - Clinica chimica acta, 2003 - Elsevier
Background: Homocysteine is a cardiovascular disease risk factor. We investigated, both in
subjects with past plasma total homocysteine (tHcy) test indications and healthy adults, the …

Total plasma homocysteine: The mediator/marker controversy continues

DW Jacobsen - Clinical chemistry, 2009 - academic.oup.com
Featured Article: Jacobsen DW, Gatautis VJ, Green R, Robinson K, Savon SR, Secic M, et al.
Rapid HPLC determination of total homocysteine and other thiols in serum and plasma: sex …

Validation of an immunoassay for measurement of plasma total homocysteine

K Marangon, D O'Byrne, S Devaraj… - American journal of …, 1999 - academic.oup.com
Hyperhomocysteinemia is an evolving cardiovascular risk factor. It is imperative that a
simple, precise, and accurate assay be available in the clinical laboratory. The aim of this …

Methods for homocysteine analysis and biological relevance of the results

V Ducros, K Demuth, MP Sauvant, M Quillard… - … of Chromatography B, 2002 - Elsevier
It is now widely accepted that increased total plasma homocysteine (tHcy) is a risk factor for
cardiovascular disease. Hyperhomocysteinemia can be caused by impaired enzyme …

[HTML][HTML] When to measure plasma homocysteine and how to place it in context: The homocystinurias

M Huemer - Journal of mother and child, 2020 - sciendo.com
This review presents clinical patterns that should trigger homocysteine measurement in
blood, as well as the further diagnostic work-up focused on inborn errors of metabolism and …

Method comparison for total plasma homocysteine between the Abbott IMx analyzer and an HPLC assay with internal standardization

CM Pfeiffer, D Twite, J Shih… - Clinical …, 1999 - academic.oup.com
Method Comparison for Total Plasma Homocysteine between the Abbott IMx Analyzer and an
HPLC Assay with Internal Standardization | Clinical Chemistry | Oxford Academic Skip to Main …

Influence of vitamin-optimized plasma homocysteine cutoff values on the prevalence of hyperhomocysteinemia in healthy adults

MR Fokkema, JM Weijer, DAJ Dijck-Brouwer… - Clinical …, 2001 - academic.oup.com
Background: Hyperhomocysteinemia is a cardiovascular disease (CVD) risk factor. We
determined plasma homocysteine (Hcy) reference values at optimized vitamin status and …