Plasma total homocysteine (tHcy) determination is used in the diagnosis of homocystinuria,
in cobalamin and folate deficiency and in cardiovascular risk assessment. However …

Total homocysteine is defined as the sum of all homocysteine species in plasma/serum,
including free and protein-bound forms. In the present review, we compare and evaluate …

Background: Measurement of plasma total homocysteine has become common as new
methods have been introduced. A wide range of disorders are associated with increased …

Total homocysteine is the sum of all homocysteine species present in plasma. This
parameter is valuable for the diagnosis and follow up of cobalamine or folate deficiencies …

It is now widely accepted that increased total plasma homocysteine (tHcy) is a risk factor for
cardiovascular disease. Hyperhomocysteinemia can be caused by impaired enzyme …

Hyperhomocysteinemia is an evolving cardiovascular risk factor. It is imperative that a
simple, precise, and accurate assay be available in the clinical laboratory. The aim of this …

Homocysteine is a sulfur-containing amino acid generated through the demethylation of
methionine. It is largely catabolized by trans-sulfuration to cysteine, but it may also be …

Objective: To summarize recent developments in our understanding of homocysteine as a
clinically relevant and independent predictor of vaso-occlusive disease (including …

Several recent studies have indicated that an increased concentration of plasma
homocysteine is an independent risk factor for the premature development of vascular …

Background: Studies investigating the relationship between plasma total homocysteine
(tHcy) and vascular disease usually rely on a single measurement. Little information is …