Background Human embryonic stem (hES) cells are a promising source for transplantation
to replace diseased or damaged tissue, but their differentiated progeny express human …

Human embryonic stem (hES) cell lines are of great potential in cell transplantation therapy.
However, recipients of such allogeneic transplants probably need treatment with …

Previous studies have performed internal matching of HLA and ABO blood type data from
either cadaveric organ donors (Taylor et al., 2005) or a cord blood bank (Nakajima et al …

Background Differentiated cells derived from pluripotent human embryonic stem (hES) cells
offer the opportunity for new transplantation therapies. However, hES cells and their …

ContextPreimplantation genetic diagnosis (PGD) has become an option for couples for
whom termination of an affected pregnancy identified by traditional prenatal diagnosis is …

Given recent improvements in the technology of transplantation and histocompatibility
testing, it is now possible to contemplate using related or unrelated allogeneic hematologic …

Background Transplantation of bone marrow from unrelated donors is limited by a lack of
HLA-matched donors and the risk of graft-versus-host disease (GVHD). Placental blood from …

In just a few years hundreds of human embryonic stem cell (hESC) lines have been
established in laboratories around the world and many programmes of research initiated to …

Background Hematopoietic stem-cell transplantation (HSCT) is a potentially lifesaving
therapy for several blood cancers and other diseases. For patients without a suitable related …

Recent progress in deriving human embryonic stem (hES) cells and defining their capacity
to differentiate has inspired hope that they could become a source of replacement cells for …