[HTML][HTML] Combinational proanthocyanidins and resveratrol synergistically inhibit human breast cancer cells and impact epigenetic–mediating machinery

Y Gao, TO Tollefsbol - International journal of molecular sciences, 2018 - mdpi.com
Breast cancer is the second most common cancer and the second leading cause of death
from cancer among women in the United States (US). Cancer prevention and therapy …

Grape and wine polyphenols down-regulate the expression of signal transduction genes and inhibit the growth of estrogen receptor–negative MDA-MB231 tumors in …

F Hakimuddin, K Tiwari, G Paliyath, K Meckling - Nutrition research, 2008 - Elsevier
The antitumor properties of the Merlot grape (and Merlot wine) polyphenols were evaluated
in relation to their ability to modulate gene expression in developing tumors using an …

Phytoestrogens in menopausal supplements induce ER-dependent cell proliferation and overcome breast cancer treatment in an in vitro breast cancer model

MBM van Duursen, EEJW Smeets, JCW Rijk… - Toxicology and applied …, 2013 - Elsevier
Breast cancer treatment by the aromatase inhibitor Letrozole (LET) or Selective Estrogen
Receptor Modulator Tamoxifen (TAM) can result in the onset of menopausal symptoms …

Phytoestrogen concentration determines effects on DNA synthesis in human breast cancer cells

C Wang, MS Kurzer - 1997 - Taylor & Francis
Thirteen isoflavonoids, flavonoids, and lignans, including some known phytoestrogens, were
evaluated for their effects on DNA synthesis in estrogen‐dependent (MCF‐7) and …

Estrogen receptor-α and aryl hydrocarbon receptor involvement in the actions of botanical estrogens in target cells

P Gong, Z Madak-Erdogan, JA Flaws… - Molecular and cellular …, 2016 - Elsevier
Botanical estrogen (BE) dietary supplements are consumed by women as substitutes for
loss of endogenous estrogens at menopause. To examine the roles of estrogen receptor α …

Estrogenic biological activity and underlying molecular mechanisms of green tea constituents

R Kiyama - Trends in Food Science & Technology, 2020 - Elsevier
Background Green tea is produced from the tea plant Camellia sinensis without
fermentation, and contains characteristic constituents, which are associated with health …

Anti-estrogenic activity of a human resveratrol metabolite

R Ruotolo, L Calani, E Fietta, F Brighenti… - Nutrition, Metabolism …, 2013 - Elsevier
Background and aims Resveratrol, the most investigated dietary compound in studies aimed
at linking wine consumption to human health, is an extremely minor component of this …

Synthesis, structure, and estrogenic activity of 4-amino-3-(2-methylbenzyl) coumarins on human breast carcinoma cells

Y Jacquot, I Laïos, A Cleeren, D Nonclercq… - Bioorganic & medicinal …, 2007 - Elsevier
A number of coumarins exhibit interesting pharmacological activities and are therefore of
therapeutic use. We report here the synthesis and the structural analysis of new N …

Estrogenic and antiproliferative activities on MCF-7 human breast cancer cells by flavonoids

JC Le Bail, F Varnat, JC Nicolas, G Habrioux - Cancer Letters, 1998 - Elsevier
The interaction between the estrogen receptor and a variety of flavonoids was studied in the
presence or absence of estradiol using a stably-transfected human breast cancer cell line …

Possible role of phytoestrogens in breast cancer via GPER-1/GPR30 signaling

L Molina, FA Bustamante, KD Bhoola… - Clinical …, 2018 - portlandpress.com
Estrogens generated within endocrine organs and the reproductive system act as ligands for
at least three types of estrogen receptors. Estrogen receptors α (ERα) and β (ERβ) belong to …