Estrogenic and antiestrogenic activities of flavonoidphytochemicals through estrogen receptorbinding-dependent and-independent mechanisms

BM Collins-Burow, ME Burow, BN Duong… - Nutrition and …, 2000 - Taylor & Francis
Members of the flavonoid class of phytochemicals have previously been demonstrated to
possess estrogenic activity in a number of hormonally responsive systems. We have …

Glucuronidation does not suppress the estrogenic activity of quercetin in yeast and human breast cancer cell model systems

R Ruotolo, L Calani, F Brighenti, A Crozier… - Archives of Biochemistry …, 2014 - Elsevier
Several plant-derived molecules, referred to as phytoestrogens, are thought to mimic the
actions of endogenous estrogens. Among these, quercetin, one of the most widespread …

Detection of weak estrogenic flavonoids using a recombinant yeast strain and a modified MCF7 cell proliferation assay

V Breinholt, JC Larsen - Chemical research in toxicology, 1998 - ACS Publications
A newly developed recombinant yeast strain, in which the human estrogen receptor has
been stably integrated into the genome of the yeast, was used to gain information on the …

The red wine phenolics piceatannol and myricetin act as agonists for estrogen receptor α in human breast cancer cells

M Maggiolini, AG Recchia, D Bonofiglio… - Journal of …, 2005 - jme.bioscientifica.com
Previous epidemiological reports have suggested that red wine intake is associated with
beneficial health effects due to the ability of certain phytochemical components to exert …

Estrogenic activity in white and red wine extracts

CM Klinge, KE Risinger, MB Watts, V Beck… - Journal of agricultural …, 2003 - ACS Publications
Red wine is enriched in resveratrol, trans-3, 5, 4 '-trihydroxystilbene, a compound in grape
skin that inhibits the development of pre-neoplastic lesions in mouse mammary tumor cells …

Phytoestrogens induce differential estrogen receptor β-mediated responses in transfected MG-63 cells

X Tang, X Zhu, S Liu, RC Nicholson, X Ni - Endocrine, 2008 - Springer
Phytoestrogens may function as partial agonists or antagonists of estrogen in many tissues
including bone. Five phytoestrogens, belonging to the isoflavones and the flavonoids …

Epigenetic control of estrogen receptor expression and tumor suppressor genes is modulated by bioactive food compounds

C Berner, E Aumüller, A Gnauck… - Annals of Nutrition and …, 2011 - karger.com
Background: The tumor suppressor genes p15INK4b and p16INK4a as well as the estrogen
receptor-α (ESR1) gene are abnormally methylated and expressed in colon cancer. The …

[HTML][HTML] Regulation of human estrogen receptor by phytoestrogens in yeast and human cells

A Breithofer, K Graumann, MS Scicchitano… - The Journal of steroid …, 1998 - Elsevier
Phytoestrogens are defined as plant substances that are structurally or functionally similar to
estrogen. They are present in many foods and their higher consumption in certain …

Evaluation of estrogenic potential of flavonoids using a recombinant yeast strain and MCF7/BUS cell proliferation assay

FA Resende, APS de Oliveira, MS de Camargo… - Plos one, 2013 - journals.plos.org
Phytoestrogens are of interest because of their reported beneficial effects on many human
maladies including cancer, neurodegeneration, cardiovascular disease and diabetes …

Tools to evaluate estrogenic potency of dietary phytoestrogens:A consensus paper from the EU Thematic Network “Phytohealth” (QLKI-2002-2453)

NM Saarinen, C Bingham, S Lorenzetti, A Mortensen… - Genes & nutrition, 2006 - Springer
Phytoestrogens are naturally occurring plantderived polyphenols with estrogenic potency.
They are ubiquitous in diet and therefore, generally consumed. Among Europeans, the diet …