Phytoestrogens can exhibit agonistic actions on estrogen-dependent gene expression in
breast cancer cells. Since several different phytoestrogens may be found within a single …

Objective To explore the effect and pathway of phytoestrogens in vitro on the growth of both
normal and malignant breast cells. Methods Normal breast MCF-10A cells and breast …

Polyphenols in foods and dietary supplements are commonly used for the prevention and
treatment of a variety of malignancies, including breast cancer. However, daily intake by …

Naringenin is present abundantly in citrus fruits and is one of the natural alternatives to
synthetic estrogen, but the mechanism of how naringenin functions is not well known. Our …

Phytoestrogens are plant constituents that possess either estrogenic or antiestrogenic
activity. Although their activities are weak as compared with human endogenous estrogens …

Erythrodiol is a terpenic compound found in a large number of plants. To test the hypotheses
that its long-term administration may influence hepatic transcriptome and this could be …

Consumption of fruits and vegetables has been associated with cancer prevention;
flavonoids are widely distributed in plant foods and considered to be the active ingredients …

In order to evaluate estrogenic compounds in natural products, an in vitro detection system
was established. For this system, the human breast cancer cell line MCF7 was stably …

Estrogen receptor α (ERα) mediates 17β‐estradiol (E2) actions through the transcription of
E2‐sensitive target genes. In addition, rapid non‐genomic signaling (eg, MAPK/ERK) …

High consumption of phytoestrogen-rich food correlates with reduced incidence of breast
cancer. However, the effect of phytoestrogens on growth of pre-existing breast tumors …