The estrogen receptors (ERs) ERα and ERβ mediate the actions of endogenous estrogens
as well as those of botanical estrogens (BEs) present in plants. BEs are ingested in the diet …

There is considerable interest in the role (s) of plant-derived compounds such as
bioflavonoids in regulating steroid hormone action in mammals, and in particular, the …

Flavonoids have been described as health‐promoting, disease‐preventing dietary
components. In vivo and in vitro experiments also support a protective effect of flavonoids to …

Resveratrol and kaempferol are natural chemopreventative agents that are also aryl
hydrocarbon receptor (AHR) antagonists and estrogen receptor (ER) agonists. In this study …

Background Estrogen receptor (ER) is a transcription factor that affects the expression of
some genes involved in the progression and development of breast cancer (BC). Hesperetin …

The in vitro effects of two closely related phyto-oestrogens daidzein and equol on the
oestrogen receptor positive human breast cancer cells MCF-7 were examined. There is …

Phytoestrogens are a group of compounds present in human diet that display estrogenic-like
properties. Several studies have demonstrated that populations who consume large …

The initial step in estrogen-regulated transcription is the binding of a ligand to its cognate
receptors, named estrogen receptors (ERα and ERβ). Phytochemicals present in foods and …

The in vivo estrogenic potential of the flavonoids apigenin, kaempferol, genistein and equol
was investigated in immature female mice. Genistein and equol, administered by gavage for …

Phytoestrogens are phenolic compounds derived from plants and exert an estrogenic as
well as an antiestrogenic effect and also various biological efficacies. Chemopreventive …