Comparative study on the nuclear hormone receptor activity of various phytochemicals and their metabolites by reporter gene assays using Chinese hamster ovary …

S Takeuchi, T Takahashi, Y Sawada, M Iida… - Biological and …, 2009 - jstage.jst.go.jp
Phytochemicals are naturally present in a wide variety of plants, and have been suggested
to exert a number of effects beneficial to human health. Several phytochemicals possess …

Resveratrol, a natural product derived from grape, exhibits antiestrogenic activity and inhibits the growth of human breast cancer cells

R Lu, G Serrero - Journal of cellular physiology, 1999 - Wiley Online Library
Resveratrol is a natural phytoalexin compound found in grapes and other food products. In
this study, the effect of resveratrol on the growth of human breast cancer cells was …

Phytoestrogens: involvement in breast and prostate cancer

JH Mitchell - … and Functional Foods.(Wildsmith, R., ed.), 2001 - api.taylorfrancis.com
The increased awareness of the role that diet plays in human and animal health has led to
the recognition that some non-nutrient components of foods may provide protection against …

Receptor binding and transactivation activities of red clover isoflavones and their metabolites

A Pfitscher, E Reiter, A Jungbauer - The Journal of steroid biochemistry and …, 2008 - Elsevier
Red clover extracts contain a variety of isoflavones, which have affinity toward estrogen
receptor alpha (ERα), estrogen receptor beta (ERβ), androgen receptor (AR), and …

The citrus‐derived flavonoid naringenin exerts uterotrophic effects in female mice at human relevant doses

VM Breinholt, GW Svendsen… - Basic & clinical …, 2004 - Wiley Online Library
Gavage administration of the citrus flavonoid naringenin, 3′, 4, 5, 7‐tetrahydroxyflavanon
for 4 consecutive days, to immature female mice (postnatal day 17–20) at 4 or 100 mg/kg b …

Impact of lower concentrations of phytoestrogens on the effects of estradiol in breast cancer cells

FP Chen, MH Chien, IYY Chern - Climacteric, 2015 - Taylor & Francis
Objective To explore the impact of lower concentrations of phytoestrogens on 17β-estradiol
(E2) in the growth of MCF-7 breast cells. Methods MCF-7 cells were treated with E2 (10− 8 …

Potential risks and benefits of phytoestrogen-rich diets

Cassidy - International Journal for Vitamin and Nutrition …, 2003 - econtent.hogrefe.com
Interest in the physiological role of bioactive compounds present in plants has increased
dramatically over the last decade. Of particular interest in relation to human health are the …

Naringenin-type flavonoids show different estrogenic effects in mammalian and teleost test systems

O Zierau, J Hamann, S Tischer, P Schwab… - Biochemical and …, 2005 - Elsevier
The estrogenic activity of several intermediary plant compounds has raised concern about
possible risks of unwanted interference with endocrine regulation, but on the other hand …

[HTML][HTML] Flavonoid effects relevant to cancer

DM Brownson, NG Azios, BK Fuqua… - The Journal of …, 2002 - Elsevier
Flavonoids, such as daidzein and genistein, present in dietary plants like soybean, have
unique chemical properties with biological activity relevant to cancer. Many flavonoids and …

Estrogen up-regulates apolipoprotein E (ApoE) gene expression by increasing ApoE mRNA in the translating pool via the estrogen receptor α-mediated pathway

RAK Srivastava, N Srivastava, M Averna, RC Lin… - Journal of Biological …, 1997 - ASBMB
The antiatherogenic property of estrogens is mediated via at least two mechanisms: first by
affecting plasma lipoprotein profiles, and second by affecting the components of the vessel …