Plant‐derived phytoestrogens and estrogens in hormone replacement therapies have
overlapping yet sometimes divergent effects on the incidence of breast cancer and …

Structure-dependent estrogen receptor α (ERα) agonist and antagonist activities of synthetic
and natural estrogenic compounds were investigated in human HepG2, MDA-MB-231 and …

Eight botanical preparations that are commonly used for the treatment of menopausal
symptoms were tested for estrogenic activity. Methanol extracts of red clover (Trifolium …

Phytoestrogens are increasingly used as dietary supplements due to their suggested health
promoting properties, but also by women for breast enhancement and relief of menopausal …

Abstract trans-Resveratrol, a polyphenolic stilbene of plant origin is structurally similar to
natural and synthetic estrogens and has been classified a phytoestrogen. Direct binding of …

To determine whether dietary berries and ellagic acid prevent 17β-estradiol (E2)–induced
mammary tumors by altering estrogen metabolism, we randomized August-Copenhagen …

Phytoestrogens are plant compounds that structurally mimic the endogenous estrogen 17β-
estradiol (E2). Despite intense investigation, the net effect of phytoestrogen exposure on the …

Phytoestrogen effects on estrogen action and tyrosine kinase activity have been proposed to
contribute to cancer prevention. To study these mechanisms, a number of phytoestrogens …

The level of estrogen receptor mRNA and cell proliferation were examined in the estrogen
responsive human breast carcinoma cell lines MCF-7 and T-47D upon the addition of …

There is renewed interest in the medicinal value of natural plant products. One group of
plant compounds, the phytoestrogens (PE), has been given considerable attention due to …