Prognostic significance of microsatellite instability in sporadic colorectal cancer

SB Lim, SY Jeong, MR Lee, JL Ku, YK Shin… - International journal of …, 2004 - Springer
Background and aims Colorectal cancers exhibiting microsatellite instability (MSI) appear to
have unique biological behavior. The influence of MSI on the prognosis of sporadic …

Low level of microsatellite instability correlates with poor clinical prognosis in stage II colorectal cancer patients

EN Mojarad, SMH Kashfi, H Mirtalebi… - Journal of …, 2016 - Wiley Online Library
The influence of microsatellite instability (MSI) on the prognosis of colorectal cancer (CRC)
requires more investigation. We assessed the role of MSI status in survival of individuals …

Low level microsatellite instability may be associated with reduced cancer specific survival in sporadic stage C colorectal carcinoma

CM Wright, OF Dent, RC Newland, M Barker… - Gut, 2005 - gut.bmj.com
Background: Colorectal cancers (CRCs) may be categorised according to the degree of
microsatellite instability (MSI) exhibited, as MSI-high (MSI-H), MSI-low (MSI-L), or …

[HTML][HTML] Predictors of disease-free survival in colorectal cancer with microsatellite instability: An AGEO multicentre study

D Tougeron, G Sickersen, G Mouillet, A Zaanan… - European Journal of …, 2015 - Elsevier
Background A microsatellite instability (MSI) phenotype is found in about 12% of colorectal
cancers (CRCs) and is associated with a low recurrence rate after curative surgery. Several …

Clinicopathologic features and prognostic analysis of MSI-high colon cancer

CC Lin, YL Lai, TC Lin, WS Chen, JK Jiang… - International journal of …, 2012 - Springer
Purpose The objectives of the study were to estimate the incidence and clarify the
clinicopathologic feature of sporadic microsatellite instability (MSI)-high (MSI-H) colon …

The prognostic significance of microsatellite instability in colorectal cancer: a Swedish multi-center study

P Rantanen, A Keränen, S Barot, S Ghazi… - International Journal of …, 2023 - Springer
Purpose About 10 to 15% of patients with sporadic colorectal cancer display mutations in
DNA mismatch repair (MMR) genes shown as microsatellite instability (MSI). Previous …

Biological features of sporadic colorectal carcinoma with high-frequency microsatellite instability: special reference to tumor proliferation and apoptosis

S Mori, Y Ogata, K Shirouzu - International journal of clinical oncology, 2004 - Springer
Background We evaluated the relationship between biological behavior and microsatellite
instability (MSI) status, with or without p53 status, in sporadic colorectal carcinoma. Methods …

[PDF][PDF] Is microsatellite instability really a good prognostic factor of colorectal cancer?

US Shin, SS Cho, SM Moon, SH Park… - Annals of …, 2014 - synapse.koreamed.org
Purpose: The aim of this study was to investigate the clinicopathologic features of and the
prognosis for colorectal cancers (CRCs) with microsatellite instabilities (MSIs). Methods …

Microsatellite instability in sporadic colon carcinomas has no independent prognostic value in a Belgian study population

V Deschoolmeester, N Van Damme, M Baay… - European Journal of …, 2008 - Elsevier
Pathological stage is currently the most important determinant of colorectal cancer
prognosis. Hence, identification of additional prognostic markers is warranted. This study …

Microsatellite instability did not predict individual survival of unselected patients with colorectal cancer

C Lamberti, S Lundin, M Bogdanow… - International journal of …, 2007 - Springer
Introduction High microsatellite instability (MSI-H) occurs in about 15% of colorectal cancers
(CRC) and clinical as well as pathological features differ from tumours exhibiting low …