Role of matrix metalloproteinases in early hypertensive vascular remodeling
M Flamant, S Placier, C Dubroca, B Esposito… - …, 2007 - Am Heart Assoc
Hypertension is associated with vascular remodeling characterized by rearrangement of
extracellular matrix proteins. To evaluate how matrix metalloproteinase (MMP)-9 contributes …
extracellular matrix proteins. To evaluate how matrix metalloproteinase (MMP)-9 contributes …
Induction and repression of collagenase-1 by keratinocytes is controlled by distinct components of different extracellular matrix compartments
BD Sudbeck, BK Pilcher, HG Welgus… - Journal of Biological …, 1997 - ASBMB
In all forms of cutaneous wounds, collagenase-1 (matrix metalloproteinase-1 (MMP-1)) is
invariably expressed by basal keratinocytes migrating over the dermal matrix. We report that …
invariably expressed by basal keratinocytes migrating over the dermal matrix. We report that …
Matrix metalloproteinase-9 is required for adequate angiogenic revascularization of ischemic tissues: potential role in capillary branching
C Johnson, HJ Sung, SM Lessner, ME Fini… - Circulation …, 2004 - Am Heart Assoc
Angiogenesis, an essential component of a variety of physiological and pathological
processes, offers attractive opportunities for therapeutic regulation. We hypothesized that …
processes, offers attractive opportunities for therapeutic regulation. We hypothesized that …
Accelerated neointima formation after vascular injury in mice with stromelysin-3 (MMP-11) gene inactivation
HR Lijnen, B Van Hoef, I Vanlinthout… - … , and vascular biology, 1999 - Am Heart Assoc
The hypothesis that stromelysin-3 (MMP-11), a unique member of the matrix
metalloproteinase (MMP) family, plays a role in neointima formation was tested with the use …
metalloproteinase (MMP) family, plays a role in neointima formation was tested with the use …
Calpain-mediated vimentin cleavage occurs upstream of MT1-MMP membrane translocation to facilitate endothelial sprout initiation
Endothelial cells normally line the vasculature and remain quiescent. However, these cells
can be rapidly stimulated to undergo morphogenesis and initiate new blood vessel …
can be rapidly stimulated to undergo morphogenesis and initiate new blood vessel …
Targeted disruption of the matrix metalloproteinase-9 gene impairs smooth muscle cell migration and geometrical arterial remodeling
ZS Galis, C Johnson, D Godin, R Magid… - Circulation …, 2002 - Am Heart Assoc
Matrix remodeling plays an important role in the physiological and pathological remodeling
of blood vessels. We specifically investigated the role of matrix metalloproteinase (MMP)-9 …
of blood vessels. We specifically investigated the role of matrix metalloproteinase (MMP)-9 …
Characterization of the distinct collagen binding, helicase and cleavage mechanisms of matrix metalloproteinase 2 and 14 (gelatinase A and MT1-MMP): the …
EM Tam, TR Moore, GS Butler, CM Overall - Journal of Biological Chemistry, 2004 - ASBMB
Matrix metalloproteinase-2 (MMP-2, gelatinase A) and membrane type (MT) 1-MMP (MMP-
14) are cooperative dynamic components of a cell surface proteolytic axis involved in …
14) are cooperative dynamic components of a cell surface proteolytic axis involved in …
[HTML][HTML] Extracellular matrix-driven matrix metalloproteinase production in endothelial cells: implications for angiogenesis
TL Haas, JA Madri - Trends in cardiovascular medicine, 1999 - Elsevier
The process of new blood vessel growth, angiogenesis, involves orchestrated alterations in
endothelial cell interactions with adjacent cells and with components of the underlying …
endothelial cell interactions with adjacent cells and with components of the underlying …
Matrix metalloproteinase-13 predominates over matrix metalloproteinase-8 as the functional interstitial collagenase in mouse atheromata
T Quillard, HA Araújo, G Franck… - … , and vascular biology, 2014 - Am Heart Assoc
Objective—Substantial evidence implicates interstitial collagenases of the matrix
metalloproteinase (MMP) family in plaque rupture and fatal thrombosis. Understanding the …
metalloproteinase (MMP) family in plaque rupture and fatal thrombosis. Understanding the …
Temporal and topographic matrix metalloproteinase expression after vascular injury in mice
HR Lijnen, F Lupu, L Moons… - Thrombosis and …, 1999 - thieme-connect.com
Temporal and topographic expression of matrix metalloproteinases (MMPs) after
perivascular electric injury was studied in wild-type (WT) and urokinase-deficient (u-PA-/-) …
perivascular electric injury was studied in wild-type (WT) and urokinase-deficient (u-PA-/-) …