Recent investigations have demonstrated that polyphenolic catechins inhibit breast cancer
cell proliferation and tumor growth. However, the ER-mediated effects of the three …

Tea catechins exert many biological effects, including anticancer and antibacterial activities.
Also, it is reported that some plant flavonoids exhibit estrogenic activity. In this study, we …

Background:(−)-Epigallocatechin-3-gallate (EGCG) is the most active catechin present in
green tea, demonstrated to have chemopreventive action and to kill cancer cells selectively …

Members of the flavonoid class of phytochemicals have previously been demonstrated to
possess estrogenic activity in a number of hormonally responsive systems. We have …

Increased intake of phytoestrogens may be associated with a lower risk of cancer in the
breast and several other sites, although there is controversy surrounding this activity. One of …

Hepatic expression of apolipoprotein (apo) II is in part modulated by estrogen-mediated
stabilization of its mRNA. This stabilization is due to the estrogen-regulated mRNA …

The in vivo estrogenic potential of the flavonoids apigenin, kaempferol, genistein and equol
was investigated in immature female mice. Genistein and equol, administered by gavage for …

Estrogen receptor α (ERα) mediates 17β‐estradiol (E2) actions through the transcription of
E2‐sensitive target genes. In addition, rapid non‐genomic signaling (eg, MAPK/ERK) …

Phytoestrogens are a chemically diverse group of compounds made by plants that can have
estrogenic effects in animals. Both tumorigenic and antitumorigenic effects have been …

This study investigates the importance of the intracellular ratio of the two estrogen receptors
ERα and ERβ for the ultimate potential of the phytoestrogens genistein and quercetin to …