BACKGROUND AND AIMS In this study, we prospectively examined the clinical significance
of the microsatellite instability (MSI) phenotype in sporadic colorectal cancer, and …

BACKGROUND Widespread microsatellite instability (MSI) occurs in nearly 15% of sporadic
colorectal cancers. Large bowel carcinomas with high‐frequency MSI (MSI‐H)(instability …

Recent studies have demonstrated the presence of microsatellite instability (MSI) in tumors
from patients with hereditary nonpolyposis colorectal cancer and in a large number of …

Background: Microsatellite instability (MSI) has been identified as a factor with good
prognosis and chemosensitivity in stage III C colon cancer. The purpose of this study was to …

Background: Microsatellite instability (MSI) is seen in 10%–15% of sporadic colorectal
cancers mostly in the right colon, but the precursors of cancers with MSI remain unknown …

BACKGROUND Carcinomas of the small intestine are rare, but the risk is greatly increased
in patients with hereditary nonpolyposis colorectal cancer (HNPCC) due to an inherited …

High-level microsatellite instability (MSI-H) is demonstrated in 10 to 15% of sporadic
colorectal cancers and in most cancers presenting in the inherited condition hereditary …

Background & Aims: Microsatellite instability is a property of most tumors occurring in the
context of hereditary nonpolyposis colon cancer. Instability also occurs in 10%–15% of …

Identification of microsatellite unstable (MSI-H) colorectal cancers (CRCs) is important not
only for the identification of hereditary nonpolyposis colorectal cancer syndrome but also …

Background and aims Colorectal cancers exhibiting microsatellite instability (MSI) appear to
have unique biological behavior. The influence of MSI on the prognosis of sporadic …