BACKGROUND: Microsatellite instability (MSI) may be a molecular marker of colorectal
tumor biology. We sought to evaluate the incidence and significance of MSI in an unselected …

Background/Aim: The prognostic role of microsatellite instability (MSI) in stage II colon
cancer patients remains controversial despite the fact that it has been investigated in a …

Background/Aim: About 15-20% of colorectal cancers (CRCs) have deficiency in a mismatch
repair (MMR) protein. MMR has a high level of microsatellite instability (MSI-H). We have …

Molecular events in early colorectal cancers (CRCs) have not been well elucidated because
of the low incidence of early CRCs in clinical practice. Therefore, we studied 104 sporadic …

BACKGROUND AND METHODS: We have reviewed and pooled data from published
studies to evaluate the relationship between microsatellite instability (MSI) and colorectal …

Purpose The role of high-degree microsatellite instability (MSI-H) as a marker to predict
benefit from adjuvant chemotherapy remains unclear. Patients and Methods To help define …

Purpose: The outcome of patients with colorectal cancer is more favorable when the tumor
exhibits high-frequency microsatellite instability (MSI). Although associated with earlier …

OBJECTIVES: Microsatellite instability (MSI) is an established marker of good prognosis in
colorectal cancer (CRC). Chromosomal instability (CIN) is strongly negatively associated …

Background Up to 15% of colorectal cancers exhibit microsatellite instability (MSI), where
errors in replication go unchecked due to defects in the mismatch repair system. This study …

Several retrospective studies have shown that a high level of microsatellite instability (MSI‐
H) is an important prognostic factor of a more favorable outcome in stage II and III colorectal …