Rats were given repeated injections of 10 mg/kg of morphine and were then left undisturbed
for 24–25 days before their brains were processed for Golgi‐Cox staining. Prior exposure to …

We studied the effects of self‐administered (SA) vs. experimenter‐administered (EA)
morphine on dendritic spines in the hippocampal formation (CA1 and dentate), nucleus …

Morphine withdrawal produces a hypofunction of mesencephalic dopamine (DA) neurons
which impinge upon medium spiny neurons (MSN) of the forebrain. After chronic treatment …

The mesolimbic dopamine system, which arises in the ventral tegmental area (VTA), is an
important neural substrate for opiate reinforcement and addiction. Chronic exposure to …

Studied the action of morphine on the turnover rate of acetylcholine in 2 nuclei receiving
dopaminergic afferents, N. caudatus and N. accumbens, and measured the turnover rate of …

Morphine withdrawal produces a hypofunction of mesencephalic dopamine neurons that
impinge upon medium spiny neurons (MSN) of the forebrain. After chronic treatment (from …

The possibility that morphine exerts its reinforcing effects via an action in the nucleus
accumbens was investigated in the rat using the self-administration model and the method …

In this study, we describe a model of opiate sensitization characterized by a brief schedule of
treatment with repeated morphine administrations. In this model, we investigated the …

Morphine withdrawal was precipitated by injection of various morphine antagonists into
restricted parts of the ventricular system or by microinjection of levallorphan into specific …

The spontaneous neuronal activity of meso-accumbens dopaminergic neurons was
recorded in unanesthetized rats withdrawn from chronic morphine administration (15 days) …