Profound decrease of mesolimbic dopaminergic neuronal activity in morphine withdrawn rats.

M Diana, M Pistis, A Muntoni, G Gessa - Journal of Pharmacology and …, 1995 - ASPET
The spontaneous neuronal activity of meso-accumbens dopaminergic neurons was
recorded in unanesthetized rats withdrawn from chronic morphine administration (15 days) …

The effect of repeated administration of morphine, cocaine and ethanol on mu and delta opioid receptor density in the nucleus accumbens and striatum of the rat

J Turchan, B Przewłocka, G Toth, W Lasoń, A Borsodi… - Neuroscience, 1999 - Elsevier
The present study was carried out to evaluate the effect of morphine, cocaine and ethanol on
the density of opioid receptors in the nucleus accumbens and striatum of rat brain. The …

[引用][C] Long lasting changes in morphine‐induced mesolimbic dopamine release after chronic morphine exposure

R Spanagel, OFX Almeida, TS Shippenberg - Synapse, 1993 - Wiley Online Library
Repeated administration of morphine to rodents produces a subsequent augmentation of
the motor stimulant effects of this drug, a phenomenon termed behavioral sensitization …

The actions of opiates in the rat substantia nigra: an electrophysiological analysis

DW Hommer, A Pert - Peptides, 1983 - Elsevier
Single unit recording and micropressure ejection techniques were used to investigate the
actions of opiates on dopaminergic and non-dopaminergic neurons in the rat substantia …

Chronic morphine impairs axoplasmic transport in the rat mesolimbic dopamine system

D Beitner-Johnson, EJ Nestler - Neuroreport, 1993 - journals.lww.com
CHRONIC morphine has been shown to decrease levels of neurofilaments (NFs) in the
ventral tegmental area (VTA), which plays a critical role in the rewarding properties of …

Morphine-dopamine interaction: ventral tegmental morphine increases nucleus accumbens dopamine release

P Leone, D Pocock, RA Wise - Pharmacology Biochemistry and Behavior, 1991 - Elsevier
Microdialysis and high-performance liquid chromatography with electrochemical detection
were used to determine extracellular levels of dopamine following ventral tegmental …

Unit activity of amygdala and hippocampal neurons: effects of morphine and benzodiazepines

DT Chou, SC Wang - Brain Research, 1977 - Elsevier
The effects of morphine sulfate and two benzodiazepine derivatives, chlordiazepoxide HCl
and diazepam, were evaluated upon single unit activity of the amygdaloid nuclear complex …

Electrophysiological evidence for excitation of rat ventral tegmental area dopamine neurons by morphine

RT Matthews, DC German - Neuroscience, 1984 - Elsevier
A considerable body of evidence indicates that opiates have an important influence on
midbrain dopaminergic neurons. However, little data exist concerning the effects of opiates …

Repeated and chronic morphine administration causes differential long-lasting changes in dopaminergic neurotransmission in rat striatum without changing its δ-and …

GHK Tjon, TJ De Vries, E Ronken… - European journal of …, 1994 - Elsevier
Repeated, once daily morphine treatment (14 days) as well as chronic morphine
administration (6 days) caused a rebound reduction in the electrically evoked release of [3 …

The effect of morphine applied locally to mesencephalic dopamine cell bodies on spontaneous motor activity in the rat

EM Joyce, SD Iversen - Neuroscience letters, 1979 - Elsevier
The effect of local application of morphine (5 μg) into the ventral tegmental area (VTA) or
substantia nigra, pars compacta (SN c) on spontaneous activity was studied in the rat …