Fluorogenic label for biomolecular imaging
Traditional small-molecule fluorophores are always fluorescent. This attribute can obscure
valuable information in biological experiments. Here, we report on a versatile “latent” …
valuable information in biological experiments. Here, we report on a versatile “latent” …
Bright building blocks for chemical biology
Small-molecule fluorophores manifest the ability of chemistry to solve problems in biology.
As we noted in a previous review (Lavis, LD; Raines, RT ACS Chem. Biol. 2008, 3, 142 …
As we noted in a previous review (Lavis, LD; Raines, RT ACS Chem. Biol. 2008, 3, 142 …
Fluorescent probes for sensing and imaging
T Ueno, T Nagano - Nature methods, 2011 - nature.com
Fluorescent probes for sensing and imaging | Nature Methods Skip to main content Thank you
for visiting nature.com. You are using a browser version with limited support for CSS. To obtain …
for visiting nature.com. You are using a browser version with limited support for CSS. To obtain …
The chemistry of small-molecule fluorogenic probes
JB Grimm, LM Heckman, LD Lavis - Progress in molecular biology and …, 2013 - Elsevier
Chemical fluorophores find wide use in biology to detect and visualize different phenomena.
A key advantage of small-molecule dyes is the ability to construct compounds where …
A key advantage of small-molecule dyes is the ability to construct compounds where …
Development of photostable fluorophores for molecular imaging
Highlights•Modern microscopy methods require fluorescent labels with increased
photostability.•The photobleaching of fluorophores often involves the first triplet-excited state …
photostability.•The photobleaching of fluorophores often involves the first triplet-excited state …
Chemistry is dead. Long live chemistry!
LD Lavis - Biochemistry, 2017 - ACS Publications
Chemistry, once king of fluorescence microscopy, was usurped by the field of fluorescent
proteins. The increased demands of modern microscopy techniques on the “photon budget” …
proteins. The increased demands of modern microscopy techniques on the “photon budget” …
Fluorogenic labeling strategies for biological imaging
The spatiotemporal fluorescence imaging of biological processes requires effective tools to
label intracellular biomolecules in living systems. This review presents a brief overview of …
label intracellular biomolecules in living systems. This review presents a brief overview of …
Chemical tools for biomolecular imaging
N Johnsson, K Johnsson - ACS chemical biology, 2007 - ACS Publications
The visualization of biologically relevant molecules and activities inside living cells
continues to transform cell biology into a truly quantitative science. However, despite the …
continues to transform cell biology into a truly quantitative science. However, despite the …
Advances in the chemistry of small molecule fluorescent probes
LM Wysocki, LD Lavis - Current opinion in chemical biology, 2011 - Elsevier
Small molecule fluorophores are essential tools for chemical biology. A benefit of synthetic
dyes is the ability to employ chemical approaches to control the properties and direct the …
dyes is the ability to employ chemical approaches to control the properties and direct the …
Dual‐functionalisation of fluorophores for the preparation of targeted and selective probes
N Trinh, KA Jolliffe, EJ New - … Chemie International Edition, 2020 - Wiley Online Library
A key current challenge in biological research is the elucidation of the that roles chemicals
and chemical reactions play in cellular function and dysfunction. Of the available cellular …
and chemical reactions play in cellular function and dysfunction. Of the available cellular …