Studied the action of morphine on the turnover rate of acetylcholine in 2 nuclei receiving
dopaminergic afferents, N. caudatus and N. accumbens, and measured the turnover rate of …

Using local injections of drugs and hemisection experiments, a comparison was made of the
actions of morphine on the dopaminergic nigrostriatal system of the rat and mouse. In the rat …

Experiments were performed on lightly pentobarbital anaesthetized Sprague-Dawley rats.
Intracarotid injection of morphine (3–6 mg/kgL) was found to inhibit the spontaneous unitary …

Morphine increased levels of acetylcholine in mouse striatum in a dose-dependent manner,
the increase occuring at the lowest dose previously found to produce analgesia and …

Administration of morphine (20 mg/kg ip) resulted in an increase in the rate of dopamine
(DA) loss by ca. 40% in the forebrain cortex of rats, when the drug was administered 30 min …

Repeated morphine administration reversed the acute effects of morphine in rats, eg
catalepsy and akinesia, and induced symptoms suggesting an activation of dopaminergic …

Numerous studies have reported that morphine administration has a variety of effects on the
cholinergic system. These include studies on the level, turnover and release of acetylcholine …

Administration of morphine results in efflux of dopamine provided that the nerve impulse flow
of the dopaminergic neurones is impaired. In the present study we investigated whether the …

Intravenous (IV) administration of 10 ug/kg of morphine sulfate increased the firing rate of
Type A dopamine neurons but decreased the extracellular activity of Type B dopamine cells …

On the basis of biochemical indices of dopamine (DA) nerve activity (decline of DA after
inhibition of tyrosine hydroxylase, accumulation of DOPA after inhibition of DOPA …