The chemistry of small-molecule fluorogenic probes
JB Grimm, LM Heckman, LD Lavis - Progress in molecular biology and …, 2013 - Elsevier
Chemical fluorophores find wide use in biology to detect and visualize different phenomena.
A key advantage of small-molecule dyes is the ability to construct compounds where …
A key advantage of small-molecule dyes is the ability to construct compounds where …
Advances in the chemistry of small molecule fluorescent probes
LM Wysocki, LD Lavis - Current opinion in chemical biology, 2011 - Elsevier
Small molecule fluorophores are essential tools for chemical biology. A benefit of synthetic
dyes is the ability to employ chemical approaches to control the properties and direct the …
dyes is the ability to employ chemical approaches to control the properties and direct the …
Bright building blocks for chemical biology
Small-molecule fluorophores manifest the ability of chemistry to solve problems in biology.
As we noted in a previous review (Lavis, LD; Raines, RT ACS Chem. Biol. 2008, 3, 142 …
As we noted in a previous review (Lavis, LD; Raines, RT ACS Chem. Biol. 2008, 3, 142 …
Lessons in organic fluorescent probe discovery
Fluorescent probes have gained profound use in biotechnology, drug discovery, medical
diagnostics, molecular and cell biology. The development of methods for the translation of …
diagnostics, molecular and cell biology. The development of methods for the translation of …
Rational design of small molecule fluorescent probes for biological applications
Fluorescent small molecules are powerful tools for visualizing biological events, embodying
an essential facet of chemical biology. Since the discovery of the first organic fluorophore …
an essential facet of chemical biology. Since the discovery of the first organic fluorophore …
Fluorescent probes for sensing and imaging
T Ueno, T Nagano - Nature methods, 2011 - nature.com
Fluorescent probes for sensing and imaging | Nature Methods Skip to main content Thank you
for visiting nature.com. You are using a browser version with limited support for CSS. To obtain …
for visiting nature.com. You are using a browser version with limited support for CSS. To obtain …
Bright ideas for chemical biology
Small-molecule fluorescent probes embody an essential facet of chemical biology. Although
numerous compounds are known, the ensemble of fluorescent probes is based on a modest …
numerous compounds are known, the ensemble of fluorescent probes is based on a modest …
Chemistry is dead. Long live chemistry!
LD Lavis - Biochemistry, 2017 - ACS Publications
Chemistry, once king of fluorescence microscopy, was usurped by the field of fluorescent
proteins. The increased demands of modern microscopy techniques on the “photon budget” …
proteins. The increased demands of modern microscopy techniques on the “photon budget” …
Fluorogenic label for biomolecular imaging
Traditional small-molecule fluorophores are always fluorescent. This attribute can obscure
valuable information in biological experiments. Here, we report on a versatile “latent” …
valuable information in biological experiments. Here, we report on a versatile “latent” …
Teaching old dyes new tricks: biological probes built from fluoresceins and rhodamines
LD Lavis - Annual review of biochemistry, 2017 - annualreviews.org
Small-molecule fluorophores, such as fluorescein and rhodamine derivatives, are critical
tools in modern biochemical and biological research. The field of chemical dyes is old; …
tools in modern biochemical and biological research. The field of chemical dyes is old; …