Profound decrease of mesolimbic dopaminergic neuronal activity in morphine withdrawn rats.
The spontaneous neuronal activity of meso-accumbens dopaminergic neurons was
recorded in unanesthetized rats withdrawn from chronic morphine administration (15 days) …
recorded in unanesthetized rats withdrawn from chronic morphine administration (15 days) …
Lasting reduction in mesolimbic dopamine neuronal activity after morphine withdrawal
The activity of mesolimbic dopaminergic neurons was investigated in rats at various times
after a chronic regimen of morphine, which produced, upon suspension, a marked somatic …
after a chronic regimen of morphine, which produced, upon suspension, a marked somatic …
Dopaminergic neurons: effect of acute and chronic morphine administration on single cell activity and transmitter metabolism
MC Nowycky, JR Walters, RH Roth - Journal of Neural Transmission, 1978 - Springer
At various time points following acute and chronic administration of morphine to rats,
dopamine transmitter metabolism and neuronal activity were determined. Following acute …
dopamine transmitter metabolism and neuronal activity were determined. Following acute …
Electrophysiological evidence for excitation of rat ventral tegmental area dopamine neurons by morphine
RT Matthews, DC German - Neuroscience, 1984 - Elsevier
A considerable body of evidence indicates that opiates have an important influence on
midbrain dopaminergic neurons. However, little data exist concerning the effects of opiates …
midbrain dopaminergic neurons. However, little data exist concerning the effects of opiates …
Retardation of cerebral dopamine turnover after morphine withdrawal and its enhanced acceleration by acute morphine administration in rats
LMJ Attila, L Ahtee - Naunyn-Schmiedeberg's archives of pharmacology, 1984 - Springer
To clarify the effects of withdrawal from chronic morphine treatment on cerebral dopamine
(DA) turnover, we have measured the α-methyl-p-tyrosine (αMT)-induced depletion of DA in …
(DA) turnover, we have measured the α-methyl-p-tyrosine (αMT)-induced depletion of DA in …
[PDF][PDF] Changes in brain monoamine metabolism during withdrawal from chronic oral self-administration of morphine and in response to a morphine challenge in the …
L Ahtee, LMJ Attila, KR Carlson, H Haikala - Journal of Pharmacology and …, 1989 - Citeseer
Accordingly, in the present experiment young Wistar rats drank increasing
concentrations(0.1-0.5 mg/mI) of morphine in water, or water alone, for 37 days. Half the rats …
concentrations(0.1-0.5 mg/mI) of morphine in water, or water alone, for 37 days. Half the rats …
The effects of low doses of morphine on the activity of dopamine-containing cells and on behavior
NL Ostrowski, CB Hatfield, AR Caggiula - Life sciences, 1982 - Elsevier
Intravenous (IV) administration of 10 ug/kg of morphine sulfate increased the firing rate of
Type A dopamine neurons but decreased the extracellular activity of Type B dopamine cells …
Type A dopamine neurons but decreased the extracellular activity of Type B dopamine cells …
The effect of morphine applied locally to mesencephalic dopamine cell bodies on spontaneous motor activity in the rat
EM Joyce, SD Iversen - Neuroscience letters, 1979 - Elsevier
The effect of local application of morphine (5 μg) into the ventral tegmental area (VTA) or
substantia nigra, pars compacta (SN c) on spontaneous activity was studied in the rat …
substantia nigra, pars compacta (SN c) on spontaneous activity was studied in the rat …
Effect of apomorphine and nigrostriatal lesions on aggression and striatal dopamine turnover during morphine withdrawal: evidence for dopaminergic supersensitivity …
G Gianutsos, MD Hynes, SK Puri, RB Drawbaugh… - …, 1974 - Springer
Reliable aggression was seen in rats which were grouped 30 days after undergoing
continuous withdrawal from morphine. This withdrawal aggression, associated with long …
continuous withdrawal from morphine. This withdrawal aggression, associated with long …
Morphine withdrawal syndrome: differential participation of structures located within the amygdaloid complex and striatum of the rat
B Calvino, J Lagowska, Y Ben-Ari - Brain research, 1979 - Elsevier
The participation of amygdaloid and striatal structures in the various signs of morphine
withdrawal syndrome (MWS) has been investigated using two complementary approaches …
withdrawal syndrome (MWS) has been investigated using two complementary approaches …
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